Current prognostic and diagnostic tests for prostate cancer are not able to accurately distinguish between aggressive and latent cancer. Members of the transforming growth factor-β (TGFB) family are known to be important in regulating prostate cell growth and some have been shown to be dysregulated in prostate cancer. Therefore, the aims of this study were to examine expression of TGFB family members in primary prostate tumour tissue and the phenotypic effect of activins on prostate cell growth. Tissue cores of prostate adenocarcinoma and normal prostate were immuno-stained and protein expression was compared between samples with different Gleason grades. The effect of exogenous treatment with, or overexpression of, activins on prostate cel...
Prostate cancer (PCa) is an increasing health issue worldwide. It is of a particular concern in New ...
Mutational changes coupled with endocrine, paracrine, and/or autocrine signals regulate cell divisio...
The role and function of the members of the TGFβ superfamily has been a substantial area of research...
Current prognostic and diagnostic tests for prostate cancer are not able to accurately distinguish b...
The Transforming Growth Factor β (TGF β) superfamily is involved with regulating many biological and...
Prostate cancer (PCa) is the most diagnosed cancer in New Zealand men and is one of the leading caus...
In recent years, a significant amount of research has examined the controversial role of activin A i...
textabstractLocal androgen synthesis in prostate cancer (PC) may contribute to the development of ca...
The possible role of activin in the regulation of malignant prostatic growth was studied using RNAas...
AbstractVentral prostate development occurs by branching morphogenesis and is an androgen-dependent ...
Mutational changes coupled with endocrine, paracrine, and/or autocrine signals regulate cell divisio...
Metastasis is a main cause of death in prostate cancer (PCa). To dissect the molecular cues from can...
Prostate cancer (PCa) is a common malignancy being the second most diagnosed cancer and sixth leadin...
Activin, a member of the TGF-β superfamily, is involved in many physiological processes, such as emb...
The healthy prostate is a relatively quiescent tissue. Yet, prostate epithelium overgrowth is a comm...
Prostate cancer (PCa) is an increasing health issue worldwide. It is of a particular concern in New ...
Mutational changes coupled with endocrine, paracrine, and/or autocrine signals regulate cell divisio...
The role and function of the members of the TGFβ superfamily has been a substantial area of research...
Current prognostic and diagnostic tests for prostate cancer are not able to accurately distinguish b...
The Transforming Growth Factor β (TGF β) superfamily is involved with regulating many biological and...
Prostate cancer (PCa) is the most diagnosed cancer in New Zealand men and is one of the leading caus...
In recent years, a significant amount of research has examined the controversial role of activin A i...
textabstractLocal androgen synthesis in prostate cancer (PC) may contribute to the development of ca...
The possible role of activin in the regulation of malignant prostatic growth was studied using RNAas...
AbstractVentral prostate development occurs by branching morphogenesis and is an androgen-dependent ...
Mutational changes coupled with endocrine, paracrine, and/or autocrine signals regulate cell divisio...
Metastasis is a main cause of death in prostate cancer (PCa). To dissect the molecular cues from can...
Prostate cancer (PCa) is a common malignancy being the second most diagnosed cancer and sixth leadin...
Activin, a member of the TGF-β superfamily, is involved in many physiological processes, such as emb...
The healthy prostate is a relatively quiescent tissue. Yet, prostate epithelium overgrowth is a comm...
Prostate cancer (PCa) is an increasing health issue worldwide. It is of a particular concern in New ...
Mutational changes coupled with endocrine, paracrine, and/or autocrine signals regulate cell divisio...
The role and function of the members of the TGFβ superfamily has been a substantial area of research...