Risk of skin cancer in people with vitiligo: a systematic review and meta-analysis

Vitiligo is a chronic disorder causing skin depigmentation with around 1% global prevalence, affecting people of all ages, skin types and genders.1 Due to the absence of melanin in lesional skin there is a theoretical concern that there might be a higher risk of skin cancer in people with vitiligo. However, some studies have shown that the genetic and autoimmune profiles of vitiligo patients may confer a degree of protection against the development of melanoma and non‐melanoma skin cancer (NMSC).2 Therefore, the aim of this systematic review was to quantify the risk of skin cancer (melanoma and NMSC) in people with vitiligo compared to those without vitiligo