Assessment of a rapid liquid-based cytology method for measuring sputum cell counts
- Martin, M.J.
- Lee, H.
- Meakin, G.
- Green, A.
- Simms, R.L.
- Reynolds, C.
- Winters, S.
- Shaw, Dominick E.
- Soomro, Irshad N.
- Harrison, Timothy W.
DOIAbstract
Differential sputum cell counting is not widely available despite proven clinical utility in the management of asthma. We compared eosinophil counts obtained using liquid-based cytology (LBC), a routine histopathological processing method, and the current standard method. Eosinophil counts obtained using LBC were a strong predictor of sputum eosinophilia (≥3%) determined by the standard method suggesting LBC could be used in the management of asthma
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