The article attempts to determine the optimal wage differentiation in Poland’s 16 regions from 1999 to 2015. In our study, optimality is a maximum level of total factor productivity. Wage differentiation was measured by the Gini coefficient. Two hypotheses were tested and confirmed: (1) the relationship between wage differentiation and TFP is described by the parabolic function with a maximum; (2) parabolic functions differ from each other, with different optimal differentiations for each region. In this article, we try to answer the question of how the optimal wage differentiation should be estimated. Is it better to group regions with a hypothetically similar optimal wage differentiation? Or is it better to use a standardised variable app...