Unconsciousness reconfigures modular brain network dynamics
- del Pozo, Sofia Morena
- Laufs, Helmut
- Bonhomme, Vincent
- Laureys, Steven
- Balenzuela, Pablo
- Tagliazucchi, Enzo Rodolfo
DOIAbstract
The dynamic core hypothesis posits that consciousness is correlated with simultaneously integrated and differentiated assemblies of transiently synchronized brain regions. We represented time-dependent functional interactions using dynamic brain networks and assessed the integrity of the dynamic core by means of the size and flexibility of the largest multilayer module. As a first step, we constrained parameter selection using a newly developed benchmark for module detection in heterogeneous temporal networks. Next, we applied a multilayer modularity maximization algorithm to dynamic brain networks computed from functional magnetic resonance imaging (fMRI) data acquired during deep sleep and under propofol anesthesia. We found that unconsci...
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