Objectives: The use of neuromuscular blocking agents (NMBAs) in pediatric acute respiratory distress syndrome (PARDS) is common but unsupported by efficacy data. We sought to compare the outcomes between patients with moderate-to-severe PARDS receiving continuous NMBA during the first 48 hours of endotracheal intubation (early NMBA) and those without. Design: Secondary analysis of data from the Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) clinical trial, a pediatric multicenter cluster randomized trial of sedation. Setting: Thirty-one PICUs in the United States. Patients: Children 2 weeks to 17 years receiving invasive mechanical ventilation (MV) for moderate-to-severe PARDS (i.e., oxygenation index >= 8 and...
Objectives: The effectiveness of noninvasive positive-pressure ventilation in preventing reintubatio...
Background: The role of neuromuscular blocking agents (NMBAs) in coronavirus disease 2019 (COVID-19)...
IMPORTANCE: Protocolized sedation improves clinical outcomes in critically ill adults, but its effec...
Objectives: The use of neuromuscular blocking agents (NMBAs) in pediatric acute respiratory distress...
Background: Paediatric acute respiratory distress syndrome (PARDS) is a manifestation of severe, lif...
BACKGROUND: Paediatric acute respiratory distress syndrome (PARDS) is a manifestation of severe, lif...
Background: Neuromuscular blockade (NMB) has been shown to improve outcome in acute respiratory dist...
Background: Paediatric acute respiratory distress syndrome (PARDS) is a manifestation of severe, lif...
Rationale: Few data exist to guide early adjunctive therapy use in pediatric acute respiratory distr...
BACKGROUND: The aim of this study is investigating the benefits and harms of neuromuscular blocking ...
BackgroundThe benefits of early continuous neuromuscular blockade in patients with acute respiratory...
Objective To determine whether neuromuscular blocking agents (NMBAs) can decrease the mortality of p...
OBJECTIVE: To measure the effect of intense neuromuscular blockade (NMB) on oxygen consumption (VO(2...
Item does not contain fulltextBACKGROUND: The benefit of using neuromuscular-blocking agents to faci...
OBJECTIVE: To determine the acute and sustained effects of early inhaled nitric oxide on some oxygen...
Objectives: The effectiveness of noninvasive positive-pressure ventilation in preventing reintubatio...
Background: The role of neuromuscular blocking agents (NMBAs) in coronavirus disease 2019 (COVID-19)...
IMPORTANCE: Protocolized sedation improves clinical outcomes in critically ill adults, but its effec...
Objectives: The use of neuromuscular blocking agents (NMBAs) in pediatric acute respiratory distress...
Background: Paediatric acute respiratory distress syndrome (PARDS) is a manifestation of severe, lif...
BACKGROUND: Paediatric acute respiratory distress syndrome (PARDS) is a manifestation of severe, lif...
Background: Neuromuscular blockade (NMB) has been shown to improve outcome in acute respiratory dist...
Background: Paediatric acute respiratory distress syndrome (PARDS) is a manifestation of severe, lif...
Rationale: Few data exist to guide early adjunctive therapy use in pediatric acute respiratory distr...
BACKGROUND: The aim of this study is investigating the benefits and harms of neuromuscular blocking ...
BackgroundThe benefits of early continuous neuromuscular blockade in patients with acute respiratory...
Objective To determine whether neuromuscular blocking agents (NMBAs) can decrease the mortality of p...
OBJECTIVE: To measure the effect of intense neuromuscular blockade (NMB) on oxygen consumption (VO(2...
Item does not contain fulltextBACKGROUND: The benefit of using neuromuscular-blocking agents to faci...
OBJECTIVE: To determine the acute and sustained effects of early inhaled nitric oxide on some oxygen...
Objectives: The effectiveness of noninvasive positive-pressure ventilation in preventing reintubatio...
Background: The role of neuromuscular blocking agents (NMBAs) in coronavirus disease 2019 (COVID-19)...
IMPORTANCE: Protocolized sedation improves clinical outcomes in critically ill adults, but its effec...