Carotid artery web and ischemic stroke: A case-control study

Coutinho, Jonathan M.
Derkatch, Sheldon
Potvin, Alphonse R.J.
Tomlinson, George
Casaubon, Leanne K.
Silver, Frank L.
Mandell, Daniel M.

Open link

Publication date

January 2017

DOI

10.1212/wnl.0000000000003464

Publisher

Ovid Technologies (Wolters Kluwer Health)

Abstract

Objective: To determine whether there is an association between carotid artery web and ischemic stroke. Methods: This was a single-center, age- and sex-matched, case-control study. Cases were consecutive patients with anterior circulation ischemic stroke of undetermined etiology (Trial of Org 10172 in Acute Stroke Treatment [TOAST] classification). Controls were consecutive patients with cerebral aneurysms, arteriovenous malformations, or primary intracerebral hemorrhages. Additional inclusion criteria were age <60 years and CT angiography of the neck. Two neuroradiologists diagnosed webs according to previously published criteria. One neuroradiologist also assessed for nonstenotic atherosclerotic plaque (carotid wall thickness ≥3 mm or int...