Percutaneous Mechanical Circulatory Support Versus Intra-Aortic Balloon Pump in Cardiogenic Shock After Acute Myocardial Infarction
- Ouweneel, Dagmar M.
- Eriksen, Erlend
- Sjauw, Krischan D.
- van Dongen, Ivo M.
- Hirsch, Alexander
- Packer, Erik J.S.
- Vis, M. Marije
- Wykrzykowska, Joanna J.
- Koch, Karel T.
- Baan, Jan
- de Winter, Robbert J.
- Piek, Jan J.
- Lagrand, Wim K.
- de Mol, Bas A.J.M.
- Tijssen, Jan G.P.
- Henriques, José P.S.
DOIAbstract
Background Despite advances in treatment, mortality in acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) remains high. Short-term mechanical circulatory support devices acutely improve hemodynamic conditions. Objectives The aim of this study was to determine whether a new percutaneous mechanical circulatory support (pMCS) device (Impella CP, Abiomed, Danvers, Massachusetts) decreases 30-day mortality when compared with an intra-aortic balloon pump (IABP) in patients with severe shock complicating AMI. Methods In a randomized, prospective, open-label, multicenter trial, 48 patients with severe CS complicating AMI were assigned to pMCS (n = 24) or IABP (n = 24). Severe CS was defined as systolic blood pressure <90 mm Hg ...
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