The analysis of clinical features in the vaccinated and unvaccinated population suffering from COVID-19 in Varaždin County

Širenje bolesti izvan granica država ili kontinenata naziva se pandemija. Najpoznatije pandemije u svijetu bile su kuga, velike boginje, španjolska gripa i trenutna bolest COVID-19. Koronavirusi su virusi koji obilježavaju 21. stoljeće. Do sada su se pojavili u 3 velika navrata: 2002. godine SARS (Teški akutni respiratorni sindrom), 2012. godine MERS (Srednje istočni respiratorni sindrom) i 2019. godine COVID-19 (Koronavirusna bolest 2019). U odnosu na ostale sezonske koronaviruse, SARS je bila prva teška i lako prenosiva nova bolest koja se pojavila u 21. stoljeću i pokazala jasnu sposobnost širenja duž ruta međunarodnog zračnog prometa. Koronavirusne infekcije su najčešće gastrointestinalne ili respiratorne. Krajem 2019. godine došlo je do pojave nove infekcije u Wuhanu te se ona vrlo brzo proširila svijetom. COVID-19 bolest se manifestira u rasponu od asimptomatske kliničke slike u 80% slučajeva, no moguća je vrlo teška i smrtonosna klinička slika. Cijepljenjem se smanjuje, ali ne nestaje, rizik od zaraze COVID-19 bolesti, a simptomi bolesti su svakako blaži. S ciljem dokazivanja blaže kliničke slike kod osoba potpuno procijepljenih protiv COVID-19 bolesti provedeno je istraživanje. U istraživanju je uključeno ukupno 6500 sudionika, od čega 3486 osoba ženskog spola i 3014 osoba muškog spola. Za potrebe ovog istraživanja korišteni su podaci prikupljeni iz Upitnika za oboljele od COVID-19 bolesti prilikom obavještavanja osoba o njihovom pozitivnom SARS-CoV-2 testu. Nakon prikupljanja podataka, odrađena je statistička obrada podataka pomoću programa Excel te su u istraživačke svrhe korišteni Upitnici osoba koje su oboljele u periodu od 1.11.2021 do 30.11.2021. godine. Istraživanje je pokazalo da većina cijepljene populacije ima blažu kliničku sliku u odnosu na necijepljenu populaciju, te da cijepljene osobe dvostruko rjeđe obolijevaju od COVID-19 bolesti. Također utvrđeno je da češće obolijeva mlađa populacija, u odnosu na stariju. Cijepljenjem protiv uzročnika neke od zaraznih bolesti, pa tako i protiv SARS-CoV-2 virusa, stvara se imunitet krda kojim se štiti cjelokupna zajednica, bilo cijepljena ili necijepljena, zdrava ili imunokompromitirana. Skepticizam prema COVID-19 cjepivima koji obavija mnoge pripadnike današnjeg društva u najvećoj je mjeri povezan sa brzinom razvoja cjepiva te je vrlo bitna zadaća medicinskih sestara da educiraju populaciju o dobrobitima i važnosti cjepivaThe spread of disease beyond the borders of countries or continents is called a pandemic. The most famous pandemics in the world were the plague, smallpox, Spanish flu, and the current COVID-19 disease. Coronaviruses are viruses that mark the 21st century. So far, they have appeared on 3 major occasions: in 2002 SARS, in 2012 MERS, and in 2019 COVID-19. Compared to other seasonal coronaviruses, SARS was the first severe and easily transmitted new disease to emerge in the 21st century and showed a clear ability to spread along international air routes. Coronavirus infections are most often gastrointestinal or respiratory. At the end of 2019, a new infection appeared in Wuhan and it spread around the world very quickly. COVID-19 disease manifests itself in the range of asymptomatic clinical features in 80% of cases, but also very severe and fatal clinical features are possible. Vaccination reduces but does not eliminate, the risk of contracting COVID-19 disease, but the symptoms of the disease are certainly much milder. To prove a milder clinical picture in people fully vaccinated people against COVID-19 disease, a study was conducted. The study included a total of 6500 participants, of which 3486 females and 3014 males. For the purposes of this study, dana was collected from the COVID-19 Disease Questionnaire that was used to inform individuals about their positive SARS-CoV-2 RT-PCR test. After data collection, statistical data processing was performed using Excel and Questionnaires of persons who fell ill in the period from 1.11.2021 to 30.11.2021. The dana was used stricktly for research purposes Research has shown that the majority of the vaccinated population has a milder clinical features compared to the unvaccinated population, and that unvaccinated individuals are twice as likely to develop COVID-19 disease. It was also found that the younger population is more likely to get sick than the older population. Vaccination against the causative agents of some infectious diseases, including the SARS-CoV-2 virus, creates a herd immunity that protects the entire community, whether vaccinated or unvaccinated, healthy or immunocompromised. The skepticism about COVID-19 vaccines that surrounds many members of today's society is largly related to the speed of vaccine development, and it is a crucial task of nurses to educate the population about the benefits and importance of vaccines