Fig 2 -

(1a) Pearson correlation coefficient heatmap between phenotypic circulating fatty acid measurements. (1b) Genetic correlation heatmap between the fatty acid measurements. (2) Additional information on the genetic instruments used in the analysis. Independent biallelic genetic variants that are associated with fatty acids below P = 5 × 10−8, have MAF > 0.1 and HWE P > 10−6 were used as instruments. Independence was assessed through clumping with r2 3) Hierarchical order of the fatty acids. DHA, docosahexaenoic acid; HWE, Hardy–Weinberg equilibrium; LA, linoleic acid; MAF, minor allele frequency; MUFA, monounsaturated fatty acid; PUFA, polyunsaturated fatty acid; SFA, saturated fatty acid; SNP, single nucleotide polymorphism; total FA, total fatty acid.