Nowadays, owing to unpredictable changes of the environment and workload variation, optimally running multiple applications in terms of quality, performance and power consumption on embedded multi-core platforms is a huge challenge. A lightweight run-time manager, linked with an automated design-time exploration and incorporated in the host processor of the platform, is required to dynamically and efficiently configure the applications according to the available platform resources (e.g. processing elements, memories, communication bandwidth), for minimising the cost (e.g. power consumption), while satisfying the constraints (e.g. deadlines). This study presents a flow linking a design-time design space explorer, coupled with platform simula...