Environmental factors that have been linked to an increased endometriosis risk include exposure to di-(2-ethylhexyl)-phthalate (DEHP), an endocrine disruptor. This study aims to investigate whether DEHP in vitro exposure in primary endometrial stromal cells (EnSC), primary endometrial epithelial cells (EnEC), and the human endometrial adenocarcinoma cell line Ishikawa properly mimics alterations described in the eutopic endometrium of women with endometriosis. Primary EnSC and EnEC, isolated from six fertile egg donors, and Ishikawa cells were exposed to DEHP (0.1, 1, and 10 µM) and were assessed for viability, endometriosis markers (IL-6, VEGF-A, HOXA10, EZH2, and LSD1), steroid receptor gene expressions (ER-1, ER-2, PR-T, PR-B, and PGRMC1...
1052-1061Wide spread use of Di-(2-ethylhexyl) phthalate (DEHP) has made it a ubiquitous contaminan...
Endocrine-disrupting chemicals (EDCs) are suspected to be associated with endometriosis (EMs). This ...
Di (2-ethylhexyl) phthalate (DEHP) is a plasticizer which is widely used in the manufacture of plast...
Raw data from viability experiments, marker expression by qPCR and invasiveness of primary endometri...
Epidemiological studies have shown the possible link between phthalates and endometrium-related gyne...
Di-(2-ethylhexyl) phthalate (DEHP) is a frequently used plasticizer that may be linked to the develo...
BACKGROUND: Emerging evidence suggests a potential role for ubiquitous environmental contaminants in...
BACKGROUND: Emerging evidence suggests a potential role for ubiquitous environmental contaminant...
Purpose: Endometriosis is a chronic debilitating inflammatory pathology which interests females in t...
BACKGROUND: Emerging evidence suggests a potential role for ubiquitous environmental contaminants in...
Objectives Di(2-ethylhexyl) phthalate (DEHP) is a common endocrine-disrupting chemical, which has po...
Background: Endometriosis is one of the common causes of infertility with very diverse etiology. In ...
Endometriosis is a common gynecological disorder affecting 6%–10% of women of reproductive age and 3...
Several available studies have already analyzed the systemic effects of endocrine-disrupting chemica...
Multiple studies have shown associations between exposure to endocrine disrupting chemicals (EDCs) a...
1052-1061Wide spread use of Di-(2-ethylhexyl) phthalate (DEHP) has made it a ubiquitous contaminan...
Endocrine-disrupting chemicals (EDCs) are suspected to be associated with endometriosis (EMs). This ...
Di (2-ethylhexyl) phthalate (DEHP) is a plasticizer which is widely used in the manufacture of plast...
Raw data from viability experiments, marker expression by qPCR and invasiveness of primary endometri...
Epidemiological studies have shown the possible link between phthalates and endometrium-related gyne...
Di-(2-ethylhexyl) phthalate (DEHP) is a frequently used plasticizer that may be linked to the develo...
BACKGROUND: Emerging evidence suggests a potential role for ubiquitous environmental contaminants in...
BACKGROUND: Emerging evidence suggests a potential role for ubiquitous environmental contaminant...
Purpose: Endometriosis is a chronic debilitating inflammatory pathology which interests females in t...
BACKGROUND: Emerging evidence suggests a potential role for ubiquitous environmental contaminants in...
Objectives Di(2-ethylhexyl) phthalate (DEHP) is a common endocrine-disrupting chemical, which has po...
Background: Endometriosis is one of the common causes of infertility with very diverse etiology. In ...
Endometriosis is a common gynecological disorder affecting 6%–10% of women of reproductive age and 3...
Several available studies have already analyzed the systemic effects of endocrine-disrupting chemica...
Multiple studies have shown associations between exposure to endocrine disrupting chemicals (EDCs) a...
1052-1061Wide spread use of Di-(2-ethylhexyl) phthalate (DEHP) has made it a ubiquitous contaminan...
Endocrine-disrupting chemicals (EDCs) are suspected to be associated with endometriosis (EMs). This ...
Di (2-ethylhexyl) phthalate (DEHP) is a plasticizer which is widely used in the manufacture of plast...