Add to ORKGThe synthesis of potent inhibitors of matrix metallo proteinases (MMPs) bearing trifluoromethyl or difluoromethyl groups in purely aliphatic positions, and the effect of the incorporation of the fluoroalkyl functions on the inhibitor potency is presented
In recent years, we have witnessed a huge progress in developing new drugs. However, the process of ...
In an effort to develop potent inhibitors of matrix metalloproteinases (MMPs), a bioinorganic approa...
The matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases involved in the d...
The synthesis of potent inhibitors of matrix metallo proteinases (MMPs) bearing trifluoromethyl or d...
The synthesis of potent inhibitors of matrix metallo proteinases (MMPs) bearing trifluoromethyl or d...
The racemic alpha-trifluoromethyl-alpha-amino-beta-sulfone hydroxamates 1 were synthesized by means ...
The racemic alpha-trifluoromethyl-alpha-amino-beta-sulfone hydroxamates 1 were synthesized by means ...
The synthesis of trifluoromethyl (Tfm) analogs of known nanomolar matrix metalloproteinases (MMPs) i...
Matrix Metalloproteinases (MMPs) are a family of enzymes that are attracting growing interest as the...
A new class of potent matrix metalloproteinase (MMP) inhibitors designed by structure-based optimiza...
Abstract Background To study MMP activity in vivo in disease, several radiolabeled MMP inhibitors fu...
The incorporation of fluorine atoms into functional molecules is of wide interest in synthetic organ...
A number of matrix metalloproteinases (MMPs) are important medicinal targets for conditions ranging ...
A number of matrix metalloproteinases (MMPs) are important medicinal targets for conditions ranging ...
Starting from the observation that the CbzNH(CH2)2 side chain of the potent MMP-2/MMP-14 inhibitor, ...
In recent years, we have witnessed a huge progress in developing new drugs. However, the process of ...
In an effort to develop potent inhibitors of matrix metalloproteinases (MMPs), a bioinorganic approa...
The matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases involved in the d...
The synthesis of potent inhibitors of matrix metallo proteinases (MMPs) bearing trifluoromethyl or d...
The synthesis of potent inhibitors of matrix metallo proteinases (MMPs) bearing trifluoromethyl or d...
The racemic alpha-trifluoromethyl-alpha-amino-beta-sulfone hydroxamates 1 were synthesized by means ...
The racemic alpha-trifluoromethyl-alpha-amino-beta-sulfone hydroxamates 1 were synthesized by means ...
The synthesis of trifluoromethyl (Tfm) analogs of known nanomolar matrix metalloproteinases (MMPs) i...
Matrix Metalloproteinases (MMPs) are a family of enzymes that are attracting growing interest as the...
A new class of potent matrix metalloproteinase (MMP) inhibitors designed by structure-based optimiza...
Abstract Background To study MMP activity in vivo in disease, several radiolabeled MMP inhibitors fu...
The incorporation of fluorine atoms into functional molecules is of wide interest in synthetic organ...
A number of matrix metalloproteinases (MMPs) are important medicinal targets for conditions ranging ...
A number of matrix metalloproteinases (MMPs) are important medicinal targets for conditions ranging ...
Starting from the observation that the CbzNH(CH2)2 side chain of the potent MMP-2/MMP-14 inhibitor, ...
In recent years, we have witnessed a huge progress in developing new drugs. However, the process of ...
In an effort to develop potent inhibitors of matrix metalloproteinases (MMPs), a bioinorganic approa...
The matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases involved in the d...