Synaptic dysregulations often result in damaging effects on the central nervous system, resulting in a wide range of brain and neurodevelopment disorders that are caused by mutations disrupting synaptic proteins. SYT1, an identified synaptotagmin protein, plays an essential role in mediating the release of calcium-triggered neurotransmitters (NT) involved in regular synaptic vesicle exocytosis. Considering the significant role of SYT1 in the physiology of synaptic neurotransmission, dysfunction and degeneration of this protein can result in a severe neurological impairment. Genetic variants lead to a newly discovered rare disorder, known as SYT1-associated neurodevelopment disorder. In this review, we will discuss in depth the function of S...
Synaptotagmin 1 (Syt 1) is an integral membrane protein responsible for sensing the calcium ion (Ca2...
In this review, we describe and discuss neurodevelopmental phenotypes arising from rare, high penetr...
Synapsin-I (SYN1) is a presynaptic phosphoprotein crucial for synaptogenesis and synaptic plasticity...
Synaptotagmin 1 (SYT1) is a critical mediator of fast, synchronous, calcium-dependent neurotransmitt...
Synaptotagmin 1 (SYT1) is a critical mediator of fast, synchronous, calcium-dependent neurotransmitt...
Synaptotagmin 1 (SYT1) is a critical mediator of fast, synchronous, calcium-dependent neurotransmitt...
Synaptotagmin-1 (SYT1) is a calcium-binding synaptic vesicle protein that is required for both exocy...
PURPOSE: Synaptotagmin-1 (SYT1) is a critical mediator of neurotransmitter release in the central ne...
International audienceMutations in many genes encoding proteins involved in various aspects of synap...
Synaptotagmins are integral synaptic vesicle membrane proteins that function as calcium sensors and ...
Synaptotagmins are integral synaptic vesicle membrane proteins that function as calcium sensors and ...
International audienceSynapsin-I (SYN1) is a presynaptic phosphoprotein crucial for synaptogenesis a...
Synapsin-I (SYN1) is a presynaptic phosphoprotein crucial for synaptogenesis and synaptic plasticity...
Synaptotagmin-11 (Syt11) is a Synaptotagmin isoform that lacks an apparent ability to bind calcium, ...
Intellectual Disability is a common and heterogeneous disorder characterized by limitations in intel...
Synaptotagmin 1 (Syt 1) is an integral membrane protein responsible for sensing the calcium ion (Ca2...
In this review, we describe and discuss neurodevelopmental phenotypes arising from rare, high penetr...
Synapsin-I (SYN1) is a presynaptic phosphoprotein crucial for synaptogenesis and synaptic plasticity...
Synaptotagmin 1 (SYT1) is a critical mediator of fast, synchronous, calcium-dependent neurotransmitt...
Synaptotagmin 1 (SYT1) is a critical mediator of fast, synchronous, calcium-dependent neurotransmitt...
Synaptotagmin 1 (SYT1) is a critical mediator of fast, synchronous, calcium-dependent neurotransmitt...
Synaptotagmin-1 (SYT1) is a calcium-binding synaptic vesicle protein that is required for both exocy...
PURPOSE: Synaptotagmin-1 (SYT1) is a critical mediator of neurotransmitter release in the central ne...
International audienceMutations in many genes encoding proteins involved in various aspects of synap...
Synaptotagmins are integral synaptic vesicle membrane proteins that function as calcium sensors and ...
Synaptotagmins are integral synaptic vesicle membrane proteins that function as calcium sensors and ...
International audienceSynapsin-I (SYN1) is a presynaptic phosphoprotein crucial for synaptogenesis a...
Synapsin-I (SYN1) is a presynaptic phosphoprotein crucial for synaptogenesis and synaptic plasticity...
Synaptotagmin-11 (Syt11) is a Synaptotagmin isoform that lacks an apparent ability to bind calcium, ...
Intellectual Disability is a common and heterogeneous disorder characterized by limitations in intel...
Synaptotagmin 1 (Syt 1) is an integral membrane protein responsible for sensing the calcium ion (Ca2...
In this review, we describe and discuss neurodevelopmental phenotypes arising from rare, high penetr...
Synapsin-I (SYN1) is a presynaptic phosphoprotein crucial for synaptogenesis and synaptic plasticity...