Breast cancer accounts for almost one quarter of all female cancers worldwide, and more than 90% of those who are diagnosed with breast cancer undergo mastectomy or breast conservation surgery. Local anesthetics effectively inhibit the invasion of cancer cells at concentrations that are used in surgical procedures. The limited treatment options for triple-negative breast cancer (TNBC) demonstrate unmet clinical needs. In this study, four local anesthetics, lidocaine, levobupivacaine, bupivacaine, and ropivacaine, were applied to two breast tumor cell types, TNBC MDA-MB-231 cells and triple-positive breast cancer BT-474 cells. In addition to the induction of apoptosis and the suppression of the cellular proliferation rate, the four local ane...
It has been reported that lidocaine is toxic to various types of cells. And a recent study has conf...
Background Retrospective studies indicate that the use of regional anaesthesia causes a reduction in...
Background: Retrospective clinical trials reported a reduced local relapse rate, as well as improved...
BACKGROUND: Previous studies have shown that local anesthetics may induce apoptosis in some cell typ...
In different retrospective studies, a protective role of regional anesthetics in reducing cancer rec...
Abstract Background Breast cancer accounts for nearly a quarter of all cancers in women worldwide, a...
Local anesthetics are frequently used in fine-needle aspiration of thyroid lesions and locoregional ...
Local anesthetics are frequently used in fine-needle aspiration of thyroid lesions and locoregional ...
Breast cancer (BC) is one of the most common types of cancer and the second leading cause of death i...
International audienceBACKGROUND: Hepatocellular carcinoma (HCC) is an aggressive cancer with limite...
Surgical removal of the primary tumor in solid cancer is an essential component of the treatment. Ho...
Des études cliniques rétrospectives ont suggéré un effet protecteur de l’anesthésie locorégionale co...
BACKGROUND Matrix-metalloproteinases (MMP) and cancer cell invasion are crucial for solid tumour me...
PMCID: PMC5742360Surgical removal of the primary tumor in solid cancer is an essential component of ...
Abstract Background: Local anesthetics (LAs) are generally considered as safe, but cytotoxicity has...
It has been reported that lidocaine is toxic to various types of cells. And a recent study has conf...
Background Retrospective studies indicate that the use of regional anaesthesia causes a reduction in...
Background: Retrospective clinical trials reported a reduced local relapse rate, as well as improved...
BACKGROUND: Previous studies have shown that local anesthetics may induce apoptosis in some cell typ...
In different retrospective studies, a protective role of regional anesthetics in reducing cancer rec...
Abstract Background Breast cancer accounts for nearly a quarter of all cancers in women worldwide, a...
Local anesthetics are frequently used in fine-needle aspiration of thyroid lesions and locoregional ...
Local anesthetics are frequently used in fine-needle aspiration of thyroid lesions and locoregional ...
Breast cancer (BC) is one of the most common types of cancer and the second leading cause of death i...
International audienceBACKGROUND: Hepatocellular carcinoma (HCC) is an aggressive cancer with limite...
Surgical removal of the primary tumor in solid cancer is an essential component of the treatment. Ho...
Des études cliniques rétrospectives ont suggéré un effet protecteur de l’anesthésie locorégionale co...
BACKGROUND Matrix-metalloproteinases (MMP) and cancer cell invasion are crucial for solid tumour me...
PMCID: PMC5742360Surgical removal of the primary tumor in solid cancer is an essential component of ...
Abstract Background: Local anesthetics (LAs) are generally considered as safe, but cytotoxicity has...
It has been reported that lidocaine is toxic to various types of cells. And a recent study has conf...
Background Retrospective studies indicate that the use of regional anaesthesia causes a reduction in...
Background: Retrospective clinical trials reported a reduced local relapse rate, as well as improved...