Efficacy and safety of prolonged dual antiplatelet therapy: a meta-analysis of 15 randomized trials enrolling 85 265 patients
- SAVARESE, GIANLUIGI
- Savonitto, Stefano
- Lund, Lars H
- PAOLILLO, STEFANIA
- MARCIANO, CATERINA
- DELLEGROTTAGLIE, SANTO
- PARENTE, ANTONIO
- TRIMARCO, BRUNO
- Luscher, Thomas F
- PERRONE FILARDI, PASQUALE
Publication date
January 2016
DOI Publisher
Oxford University Press (OUP) ISSN
2055-6837 Citation count (estimate)
5Abstract
The optimal duration of dual antiplatelet therapy (DAPT) in patients with ischaemic cardiovascular (CV) disease is still debated. Previous meta-analyses reported conflicting results about prolonged DAPT on mortality and major CV events. Aim of this study was to assess the effects of prolonged vs. no/short-term DAPT on myocardial infarction (MI), stroke, bleeding, and mortality
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