The effect of antioxidants on biochemical and morphological indicators of the piglet's blood

The work aimed to study the influence of methifen, fenarone, and methionine on the biochemical and morphological indicators of the piglet’s blood. We researched three-month-old large white piglets. 10 groups were formed, each with 5 animals: a control group and nine experimental groups. We established that antioxidants promote an increase in the erythrocyte number and the Hb level to the upper limits of physiological indicators from the 10th day of the test. On the 60th day, the erythrocyte number in the blood of piglets fed methionine varied between 7.15 ± 0.12 – 7.30 ± 0.12 B/l. This indicator was 7.34 ± 0.10 – 7.64 ± 0.11 B/l (Р < 0.05) in the group fed fenarone, and 7.64 ± 0.14 – 7.65 ± 0.11 B/l (Р < 0.05) in animals fed methifen. On the 90th day, the erythrocyte number was the highest in animals that were fed methifen at a dose of 0.9 mg/kg body weight. Relative to piglets of the C group, the aforementioned indicator increased by 12.9 %. We also found a slight growth in the activity of aminotransferases in the blood serum of piglets of the experimental groups. In addition, it was found that the studied drugs do not affect the mononuclear system. It was indicated by the number of leukocytes, which was within the limits of physiological parameters during the experiment and ranged from 10.0 ± 0.12 to 11.8 ± 0.6 G/l. The highest indicators of enzyme activity, hemoglobin content, and the number of erythrocytes in the blood of animals of the experimental groups were established on the 60th and 90th days of the trial. It manifested the best effect under methionine feeding at a dose of 4 mg/kg body weight, fenarone – 1.20 mg/kg body weight. and metifen – 0.9 mg/kg body weight