We develop the properties of the nth sequential topological complexity TCn, a homotopy invariant introduced by the third author as an extension of Farber's topological model for studying the complexity of motion planning algorithms in robotics. We exhibit close connections of TCn(X) to the Lusternik-Schnirelmann category of cartesian powers of X, to the cup length of the diagonal embedding X hooked right arrow X-n, and to the ratio between homotopy dimension and connectivity of X. We fully compute the numerical value of TCn for products of spheres, closed 1-connected symplectic manifolds and quaternionic projective spaces. Our study includes two symmetrized versions of TCn(X). The first one, unlike Farber and Grant's symmetric topological c...