Add to ORKGThe concentration of adenosine nucleotides (ATP&ADP) in the circulation may impact health and disease by controlling cellular metabolic pathways in tissues throughout the body. Fasting plasma nucleotide levels are normally relatively low in healthy subjects, but can increase by orders of magnitude in disease. High circulating nucleotide levels promote chronic purinergic signaling, which may disrupt the normal cellular metabolism in the body and initiate immune and inflammatory consequences. Strategies to control nucleotide levels in the bloodstream may therefore have therapeutic importance to halt the progression of metabolic disorders
Adenosine 5’-triphosphate (ATP) is one of the most abundant molecule in living cells serving as univ...
Copyright © 2015 Jean Sévigny et al. This is an open access article distributed under the Creative ...
Ectonucleotidases modulate inflammatory responses by balancing extracellular ATP and adenosine (ADO)...
The concept of a purinergic signalling system was first proposed by Professor Geoffrey Burnstock ove...
Purine nucleotide degradation refers to a regulated series of reactions by which human purine ribonu...
Purine nucleotides are essential basic building blocks for DNA and RNA synthesis. They can also serv...
Purines and their derivatives, most notably adenosine and ATP, are the key molecules controlling int...
Purines and their derivatives, most notably adenosine and ATP, are the key molecules controlling int...
Nucleotides and nucleosides-such as adenosine triphosphate (ATP) and adenosine-are famous for their ...
The role of ATP as an extracellular signalling molecule is now well established and evidence is accu...
Purine derivatives like adenosine 5′-triphosphate (ATP) is the powerhouse of the cell and is essenti...
The role of ATP as an extracellular signalling molecule is now well established and evidence is accu...
Human health is under constant threat of a wide variety of dangers, both self and nonself. The immun...
Human health is under constant threat of a wide variety of dangers, both self and nonself. The immun...
Nucleotides are released from all cells through regulated pathways or as a result of plasma membrane...
Adenosine 5’-triphosphate (ATP) is one of the most abundant molecule in living cells serving as univ...
Copyright © 2015 Jean Sévigny et al. This is an open access article distributed under the Creative ...
Ectonucleotidases modulate inflammatory responses by balancing extracellular ATP and adenosine (ADO)...
The concept of a purinergic signalling system was first proposed by Professor Geoffrey Burnstock ove...
Purine nucleotide degradation refers to a regulated series of reactions by which human purine ribonu...
Purine nucleotides are essential basic building blocks for DNA and RNA synthesis. They can also serv...
Purines and their derivatives, most notably adenosine and ATP, are the key molecules controlling int...
Purines and their derivatives, most notably adenosine and ATP, are the key molecules controlling int...
Nucleotides and nucleosides-such as adenosine triphosphate (ATP) and adenosine-are famous for their ...
The role of ATP as an extracellular signalling molecule is now well established and evidence is accu...
Purine derivatives like adenosine 5′-triphosphate (ATP) is the powerhouse of the cell and is essenti...
The role of ATP as an extracellular signalling molecule is now well established and evidence is accu...
Human health is under constant threat of a wide variety of dangers, both self and nonself. The immun...
Human health is under constant threat of a wide variety of dangers, both self and nonself. The immun...
Nucleotides are released from all cells through regulated pathways or as a result of plasma membrane...
Adenosine 5’-triphosphate (ATP) is one of the most abundant molecule in living cells serving as univ...
Copyright © 2015 Jean Sévigny et al. This is an open access article distributed under the Creative ...
Ectonucleotidases modulate inflammatory responses by balancing extracellular ATP and adenosine (ADO)...