POTENTIAL UTILIZATION OF SEMBUNG (Blumea balsamifera) LEAVES WITH ANALYSIS OF PHOTOCHEMICAL CONTENT, ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES

Sembung plant (Blumea balsamifera) is known to have natural antibacterial properties, which can inhibit the growth of cancer and tumors. This study explored the potential of Sembung leaves for its phytochemical analysis, antioxidant and antibacterial activity. Test of antioxidant activity showed that the n-hexane of sembung leaves extract display ability to inhibit DPPH free radical by 70% at 200 ppm concentration,while ethyl acetate extracts by 87% at 100 ppm consentration and ethanol extracts by 82% at 50 ppm and 100 ppm consentration. Antibacterial activity showed that the ethanol extract of sembung leaves display ability to inhibit the P. acnes growth with 14 mm inhibition activity at 400 µg/well concentration. The ethanol extracts of sembung leaves display ability to inhibit the S. mutans growth with 15 mm at 400 µg/well concentration. Antibacterial activity of ethanol extract of sembung leaves display ability to inhibit the S. sobrinus growth with 13 mm at 400 µg/well concentration. Based on the results, Sembung leaves (B. balsamifera) display potential as a natural antioxidant and antibacterial agent