We have previously reported an in vivo enlargement of the left hypothalamus in mood disorders using 7 T magnetic resonance imaging. The aim of this follow-up study was to find out whether the hypothalamic volume difference may be located in the mammillary bodies (MB) rather than being widespread across the hypothalamus.We developed and evaluated a detailed segmentation algorithm that allowed a reliable segmentation of the MBs, and applied it to 20 unmedicated (MDDu) and 20 medicated patients with major depressive disorder, 21 medicated patients with bipolar disorder, and 23 controls. 20 out of 23 healthy controls were matched to the MDDu. We tested for group differences in MB and hypothalamus without MB (HTh) volumes using analyses of covar...
High resolution magnetic resonance imaging and voxel-based morphometry were used to compare regional...
There are no specific structural neuropathological hallmarks found in the brain of mood disorders. I...
MRI-based reports of both abnormally increased and decreased amygdala volume in bipolar disorder (BD...
Objective The purpose of this study was to determine, in vivo, whether the hypothalamus volume is re...
Hypothalamic abnormalities in schizophrenia have been associated with endocrine dysfunctions and str...
A large body of evidence indicates that the hypothalamus is involved in pathogenetic mechanisms of m...
Volumetric differences of the hypothalamus and/or the pituitary gland tend to support involvement of...
BACKGROUND: Neuroendocrinologic investigations in bipolar disorder have suggested abnormalities in p...
BACKGROUND: Bipolar disorder has been associated with increased Hypothalamic-Pituitary-Adrenal axis ...
Several studies assessing volumetric measurements of regional brain structure in bipolar disorder ha...
BACKGROUND: Hyperactivity of the Hypothalamic-Pituitary-Adrenal Axis (HPAA) has been consistently r...
Background: Hyperactivity of the Hypothalamic-Pituitary-Adrenal Axis (HPAA) has been consistently re...
The pituitary gland (PG) is a key component of the essential endocrine systems in humans and animals...
While the frontal cortices and medial temporal lobe are well associated with schizophrenia, the invo...
Background: Increased activity of the habenula has been implicated in the etiology of major depressi...
High resolution magnetic resonance imaging and voxel-based morphometry were used to compare regional...
There are no specific structural neuropathological hallmarks found in the brain of mood disorders. I...
MRI-based reports of both abnormally increased and decreased amygdala volume in bipolar disorder (BD...
Objective The purpose of this study was to determine, in vivo, whether the hypothalamus volume is re...
Hypothalamic abnormalities in schizophrenia have been associated with endocrine dysfunctions and str...
A large body of evidence indicates that the hypothalamus is involved in pathogenetic mechanisms of m...
Volumetric differences of the hypothalamus and/or the pituitary gland tend to support involvement of...
BACKGROUND: Neuroendocrinologic investigations in bipolar disorder have suggested abnormalities in p...
BACKGROUND: Bipolar disorder has been associated with increased Hypothalamic-Pituitary-Adrenal axis ...
Several studies assessing volumetric measurements of regional brain structure in bipolar disorder ha...
BACKGROUND: Hyperactivity of the Hypothalamic-Pituitary-Adrenal Axis (HPAA) has been consistently r...
Background: Hyperactivity of the Hypothalamic-Pituitary-Adrenal Axis (HPAA) has been consistently re...
The pituitary gland (PG) is a key component of the essential endocrine systems in humans and animals...
While the frontal cortices and medial temporal lobe are well associated with schizophrenia, the invo...
Background: Increased activity of the habenula has been implicated in the etiology of major depressi...
High resolution magnetic resonance imaging and voxel-based morphometry were used to compare regional...
There are no specific structural neuropathological hallmarks found in the brain of mood disorders. I...
MRI-based reports of both abnormally increased and decreased amygdala volume in bipolar disorder (BD...