Add to ORKGKrabbe Disease (KD) is a lysosomal storage disorder characterized by the genetic deficiency of the lysosomal enzyme β-galactosyl-ceramidase (GALC). Deficit or a reduction in the activity of the GALC enzyme has been correlated with the progressive accumulation of the sphingolipid metabolite psychosine, which leads to local disruption in lipid raft architecture, diffuse demyelination, astrogliosis, and globoid cell formation. Th
Krabbe's disease (KD) is a degenerative lysosomal storage disease resulting from deficiency of β-gal...
Missense mutations in the lysosomal hydrolase β-galactocerebrosidase (GALC) account for at least 40%...
Krabbe disease (KD) is an autosomal recessive neurodegenerative disorder caused by defective beta-ga...
Krabbe disease is a severe, fatal neurodegenerative disorder caused by defects in the lysosomal enzy...
Krabbe disease (KD) is a rare autosomal recessive disorder caused by mutations in the galactocerebro...
Introduction: Krabbe disease (KD) or globoid cell leukodystrophy (GLD) is one of the lysosomal disor...
Krabbe disease (KD) is a lysosomal storage disease (LSD) caused by mutations in the galc gene. There...
Krabbe disease is a lysosomal storage disorder that affects several species including humans, mice a...
Krabbe disease is a severe, fatal neurodegenerative disorder caused by defects in the lysosomal enzy...
Neonatal AAV9-gene therapy of the lysosomal enzyme galactosylceramidase (GALC) significantly amelior...
Background: Krabbe disease (KD) or globoid cell leukodystrophy is an autosomal recessive lysosomal d...
Azzam A Maghazachi Research Department, ImmnoProfiling and Boosting, Oslo, NorwayCorrespondence: Azz...
Krabbe disease is a devastating pediatric leukodystrophy caused by mutations in the galactocerebrosi...
The lysosomal hydrolase galactocerebrosidase (GALC) catalyzes the removal of galactose from galactos...
Krabbe disease is a devastating pediatric leukodystrophy caused by mutations in the galactocerebrosi...
Krabbe's disease (KD) is a degenerative lysosomal storage disease resulting from deficiency of β-gal...
Missense mutations in the lysosomal hydrolase β-galactocerebrosidase (GALC) account for at least 40%...
Krabbe disease (KD) is an autosomal recessive neurodegenerative disorder caused by defective beta-ga...
Krabbe disease is a severe, fatal neurodegenerative disorder caused by defects in the lysosomal enzy...
Krabbe disease (KD) is a rare autosomal recessive disorder caused by mutations in the galactocerebro...
Introduction: Krabbe disease (KD) or globoid cell leukodystrophy (GLD) is one of the lysosomal disor...
Krabbe disease (KD) is a lysosomal storage disease (LSD) caused by mutations in the galc gene. There...
Krabbe disease is a lysosomal storage disorder that affects several species including humans, mice a...
Krabbe disease is a severe, fatal neurodegenerative disorder caused by defects in the lysosomal enzy...
Neonatal AAV9-gene therapy of the lysosomal enzyme galactosylceramidase (GALC) significantly amelior...
Background: Krabbe disease (KD) or globoid cell leukodystrophy is an autosomal recessive lysosomal d...
Azzam A Maghazachi Research Department, ImmnoProfiling and Boosting, Oslo, NorwayCorrespondence: Azz...
Krabbe disease is a devastating pediatric leukodystrophy caused by mutations in the galactocerebrosi...
The lysosomal hydrolase galactocerebrosidase (GALC) catalyzes the removal of galactose from galactos...
Krabbe disease is a devastating pediatric leukodystrophy caused by mutations in the galactocerebrosi...
Krabbe's disease (KD) is a degenerative lysosomal storage disease resulting from deficiency of β-gal...
Missense mutations in the lysosomal hydrolase β-galactocerebrosidase (GALC) account for at least 40%...
Krabbe disease (KD) is an autosomal recessive neurodegenerative disorder caused by defective beta-ga...