BACKGROUND: Fat mass (FM) in overweight/obese subjects has a primary role in determining low-grade chronic inflammation and, in turn, insulin resistance (IR) and ectopic lipid storage within the liver. Obesity, aging, and FM influence the growth hormone/insulin-like growth factor (IGF)-I axis, and chronic inflammation might reduce IGF-I signaling. Altered IGF-I axis is frequently observed in patients with Hepatic steatosis (HS). We tested the hypothesis that FM, or spleen volume and C-reactive protein (CRP)--all indexes of chronic inflammation--could affect the IGF-I axis status in overweight/obese, independently of HS. METHODS: The study population included 48 overweight/obese women (age 41 ± 13 years; BMI: 35.8 ± 5.8 kg/m2; range: 25.3-5...
Objectives: The mechanisms responsible for the development of nonalcoholic fatty liver disease (NAFL...
International audienceNon-alcoholic fatty liver disease (NAFLD) is commonly associated with obesity,...
Obesity is a severe public health problem worldwide, leading to an insulin-resistant state in liver,...
BACKGROUND: Fat mass (FM) in overweight/obese subjects has a primary role in determining low-grade c...
Recently the association between hepatic steatosis and sarcopenia has been described. GH/IGF-1 axis ...
Introduction Nonalcoholic fatty liver disease (NAFLD) has been described in adult GH deficiency syn...
Introduction: Non-alcoholic fatty liver disease (NAFLD) has been described in adult GH deficiency s...
Polycystic Ovary Syndrome (PCOS) is characterized by an extreme variety of phenotypes and controvers...
AbstractObjectivesThis study evaluated whether obesity in humans was associated with an increase in ...
Objective-The goal of this study was to assess the independent and collective associations of hepati...
Objective: Plasma Hepatocyte Growth Factor (HGF) is significantly elevated in obesity and may contri...
The insulin-like growth factor (IGF) system, acting in concert with other hormone axes, is important...
Background/Aims: To ascertain whether the etiology of hepatic steatosis modulates insulin resistance...
Objective To correlate circulating levels of insulin-like growth factor (IGF)-I, IGF-II, and IGF bin...
Polycystic Ovary Syndrome (PCOS) is characterized by an extreme variety of phenotypes and controvers...
Objectives: The mechanisms responsible for the development of nonalcoholic fatty liver disease (NAFL...
International audienceNon-alcoholic fatty liver disease (NAFLD) is commonly associated with obesity,...
Obesity is a severe public health problem worldwide, leading to an insulin-resistant state in liver,...
BACKGROUND: Fat mass (FM) in overweight/obese subjects has a primary role in determining low-grade c...
Recently the association between hepatic steatosis and sarcopenia has been described. GH/IGF-1 axis ...
Introduction Nonalcoholic fatty liver disease (NAFLD) has been described in adult GH deficiency syn...
Introduction: Non-alcoholic fatty liver disease (NAFLD) has been described in adult GH deficiency s...
Polycystic Ovary Syndrome (PCOS) is characterized by an extreme variety of phenotypes and controvers...
AbstractObjectivesThis study evaluated whether obesity in humans was associated with an increase in ...
Objective-The goal of this study was to assess the independent and collective associations of hepati...
Objective: Plasma Hepatocyte Growth Factor (HGF) is significantly elevated in obesity and may contri...
The insulin-like growth factor (IGF) system, acting in concert with other hormone axes, is important...
Background/Aims: To ascertain whether the etiology of hepatic steatosis modulates insulin resistance...
Objective To correlate circulating levels of insulin-like growth factor (IGF)-I, IGF-II, and IGF bin...
Polycystic Ovary Syndrome (PCOS) is characterized by an extreme variety of phenotypes and controvers...
Objectives: The mechanisms responsible for the development of nonalcoholic fatty liver disease (NAFL...
International audienceNon-alcoholic fatty liver disease (NAFLD) is commonly associated with obesity,...
Obesity is a severe public health problem worldwide, leading to an insulin-resistant state in liver,...