Metabolic syndrome and cardiovascolar risk prediction in peripheral arterial disease.
- Brevetti, Gregorio
- Laurenzano, E
- Giugliano, Giuseppe
- Lanero, S
- Brevetti, L
- Luciano, R
- Chiariello, Massimo
DOIAbstract
BACKGROUND AND AIMS: Metabolic syndrome (MetS) was reported to be associated with increased cardiovascular risk in various settings, however its prognostic impact in peripheral arterial disease (PAD) is scanty. METHODS AND RESULTS: We prospectively studied 173 patients with intermittent claudication and ankle/brachial index (ABI)<0.90, in whom MetS was defined using the criteria of both the revised version of the Adults Treatment Panel III (rATP III) and the International Diabetes Federation (IDF). Of these patients, 52.6% met the rATP III and 54.9% the IDF criteria for MetS. During a median follow-up of 31 months, 54 cardiovascular events occurred. Kaplan-Meier curves showed a greater incidence of ischemic events in patients with MetS tha...
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