The diagnostic approach to acromegaly and GH deficiency frequently includes measurement of several components of the insulin-like growth factor (IGF) system. IGF-I levels are reported to be good predictors of active and cured acromegaly, but are commonly found within the normal age-adjusted range in adult GH-deficient (GHD) patients. Circulating concentrations of IGF-binding protein-3 (IGFBP-3), acid-labile subunit (ALS), and free IGF-I reflect the GH secretory status, but their diagnostic accuracy is still debated. In this study serum levels of total and free IGF-I, IGFBP-3, ALS, and IGFBP-3-IGF-I and IGFBP-3-ALS complexes were determined in patients previously diagnosed with active (n = 67) or inactive (n = 16) acromegaly and adult GHD (n...
(IGFBP-3), IGF-I/IGFBP-3 molar ratio and urinary GH measurements in the diagnosis of adult GH defici...
Biochemical markers for remission on acromegaly activity are controversial. We studied a subset of t...
The diagnosis of childhood onset GH deficiency (GHD) is often problematic especially for idiopathi...
The diagnostic approach to acromegaly and GH deficiency frequently includes measurement of several c...
Biological markers (biomarkers) play a key role in drug development, regulatory approval and clinica...
Tuzun, Hakan/0000-0002-6376-8979WOS: 000298720200004Objective: Insulin-like growth factor-I (IGF-I) ...
In patients with growth hormone (GH) deficiency (GHD) the diagnostic value of IGF-I levels has been ...
The impact of GH deficiency and rhGH replacement therapy on IGF-I, IGFBP-3 and ALS levels has been w...
Current guidelines for the diagnosis of adult growth hormone deficiency (GHD) state that the diagnos...
The paper studied the levels IGFBP-3 in patients with acromegaly, received different therapies. The ...
Measurements of serum insulin-like growth factor I (IGF-I) and related markers are routinely used in...
The diagnosis of growth hormone (GH) deficiency (GHD) in childhood is not straightforward, being sti...
The measurement of serum immunoreactive IGFBP-3 levels has been proposed as a screening test to iden...
The criteria for biochemical control of acromegaly that will best reduce disease-related morbidity i...
OBJECTIVE Within an appropriate clinical context, GH deficiency (GHD) in adults must be demonstrated...
(IGFBP-3), IGF-I/IGFBP-3 molar ratio and urinary GH measurements in the diagnosis of adult GH defici...
Biochemical markers for remission on acromegaly activity are controversial. We studied a subset of t...
The diagnosis of childhood onset GH deficiency (GHD) is often problematic especially for idiopathi...
The diagnostic approach to acromegaly and GH deficiency frequently includes measurement of several c...
Biological markers (biomarkers) play a key role in drug development, regulatory approval and clinica...
Tuzun, Hakan/0000-0002-6376-8979WOS: 000298720200004Objective: Insulin-like growth factor-I (IGF-I) ...
In patients with growth hormone (GH) deficiency (GHD) the diagnostic value of IGF-I levels has been ...
The impact of GH deficiency and rhGH replacement therapy on IGF-I, IGFBP-3 and ALS levels has been w...
Current guidelines for the diagnosis of adult growth hormone deficiency (GHD) state that the diagnos...
The paper studied the levels IGFBP-3 in patients with acromegaly, received different therapies. The ...
Measurements of serum insulin-like growth factor I (IGF-I) and related markers are routinely used in...
The diagnosis of growth hormone (GH) deficiency (GHD) in childhood is not straightforward, being sti...
The measurement of serum immunoreactive IGFBP-3 levels has been proposed as a screening test to iden...
The criteria for biochemical control of acromegaly that will best reduce disease-related morbidity i...
OBJECTIVE Within an appropriate clinical context, GH deficiency (GHD) in adults must be demonstrated...
(IGFBP-3), IGF-I/IGFBP-3 molar ratio and urinary GH measurements in the diagnosis of adult GH defici...
Biochemical markers for remission on acromegaly activity are controversial. We studied a subset of t...
The diagnosis of childhood onset GH deficiency (GHD) is often problematic especially for idiopathi...