Add to ORKGThe synthesis, physical and analytical characterization, and crystal-state structural analysis by X-ray diffraction of three analogues of the N alpha-acylated tripeptide amide tail of oxytocin, each containing a cyclic C alpha, alpha-disubstituted glycine at position 2, have been performed. The peptides are Boc-L-Pro-Ac3c-Gly-NH2, Z-L-Pro-Ac5c-Gly-NH2 and Z-L-Pro-Ac6c-Gly-NH2. While the former is folded in a type-II beta-turn conformation at the -L-Pro-Ac3c- sequence, the two latter tripeptides form two consecutive (type-II, type-I') beta-turns. The Ac5c- and Ac6c-tripeptides are the first examples of such a highly folded structural combination in a position-2 analogue of the N alpha-acylated -L-Pro-L-Leu-Gly-NH2 sequence
The crystal structure of an acyclic pentapeptide, Boc-Gly-Gly-Leu-Aib-Val-OMe, reveals an extended c...
A series of terminally blocked peptides (to the pentamer level) from L-Ala and the cyclic C-alpha,C-...
A series of N- and C-protected, monodispersed homo-oligopeptides (to the pentamer level) from the cy...
The synthesis, physical and analytical characterization, and crystal-state structural analysis by X-...
The synthesis, physical and analytical characterization, and crystal‐state structural analysis by X‐...
An Nα-protected model tripeptide amide containing, in the central position, an α,β-dehydrophenylalan...
An N-alpha-protected model tripeptide amide containing, in the central position, an alpha,beta-dehyd...
The preparation of 11 new oxytocin analogs is described. The synthesis of the protected peptides wer...
The synthesis of seventeen novel conformationally constrained analogues of the neurohypophyseal pept...
A critical analysis of single crystal X-ray diffraction studies on a series of terminally protected ...
Two complete series of N-protected, monodispersed oligopeptide esters to the pentamer level from 1-a...
The crystal structure of the fully protected glycotripeptide N-benzyloxycrbonyl-O-(2,3,4,6-tetra-O-a...
The tripeptides Boc-Gly-Aib-m-ABA-OMe (I), Boc-beta Ala-Aib-m-ABA-OMe (II) and Boc-gamma Abu-Aib-rn-...
We report here the synthesis and molecular structure in the solid state of fully protected tripeptid...
A critical analysis of single crystal X-ray diffraction studies on a series of terminally protected ...
The crystal structure of an acyclic pentapeptide, Boc-Gly-Gly-Leu-Aib-Val-OMe, reveals an extended c...
A series of terminally blocked peptides (to the pentamer level) from L-Ala and the cyclic C-alpha,C-...
A series of N- and C-protected, monodispersed homo-oligopeptides (to the pentamer level) from the cy...
The synthesis, physical and analytical characterization, and crystal-state structural analysis by X-...
The synthesis, physical and analytical characterization, and crystal‐state structural analysis by X‐...
An Nα-protected model tripeptide amide containing, in the central position, an α,β-dehydrophenylalan...
An N-alpha-protected model tripeptide amide containing, in the central position, an alpha,beta-dehyd...
The preparation of 11 new oxytocin analogs is described. The synthesis of the protected peptides wer...
The synthesis of seventeen novel conformationally constrained analogues of the neurohypophyseal pept...
A critical analysis of single crystal X-ray diffraction studies on a series of terminally protected ...
Two complete series of N-protected, monodispersed oligopeptide esters to the pentamer level from 1-a...
The crystal structure of the fully protected glycotripeptide N-benzyloxycrbonyl-O-(2,3,4,6-tetra-O-a...
The tripeptides Boc-Gly-Aib-m-ABA-OMe (I), Boc-beta Ala-Aib-m-ABA-OMe (II) and Boc-gamma Abu-Aib-rn-...
We report here the synthesis and molecular structure in the solid state of fully protected tripeptid...
A critical analysis of single crystal X-ray diffraction studies on a series of terminally protected ...
The crystal structure of an acyclic pentapeptide, Boc-Gly-Gly-Leu-Aib-Val-OMe, reveals an extended c...
A series of terminally blocked peptides (to the pentamer level) from L-Ala and the cyclic C-alpha,C-...
A series of N- and C-protected, monodispersed homo-oligopeptides (to the pentamer level) from the cy...