Add to ORKGAntimalarial agents having a novel pharmacophore of formula (I) are herein described. These polycyclic compounds are able to inhibit chloroquine-sensitive and chloroquine-resistant strains ofPlasmodium falciparum (Pf). Furthermore, the synthesis of these compounds involves few steps from commercial products with low cost of production
Malaria is a major health problem in poverty-stricken regions where new antiparasitic drugs are urge...
International audienceAmodiaquine remains one of the most prescribed antimalarial 4-aminoquinoline. ...
Malaria is a major health problem in poverty-stricken regions where new antiparasitic drugs are urge...
Antimalarial agents having a novel pharmacophore of formula (I) are herein described. These polycycl...
The synthesis of imidazolidin-4-one derivatives of primaquine containing the five-membered ring at t...
Identification of new molecular scaffolds structurally unrelated to known antimalarials may represen...
Identification of new molecular scaffolds structurally unrelated to known antimalarials may represen...
The synthesis of imidazolidin-4-one derivatives of primaquine as potential antimalarial agents is de...
Identification of new molecular scaffolds structurally unrelated to known antimalarials may represen...
Imidazolidin-4-one derivatives of primaquine were synthesized as potential double prodrugs of the pa...
In order to develop new effective antimalarial agents, we have demonstrated that the replacement of ...
The increasing resistance of the malaria parasite P. falciparum to currently available drugs demand...
The synthesis of imidazolidin-4-one derivatives of primaquine as potential antimalarial agents is de...
Antimalarial agents structurally based on novel pharmacophores, synthesized by low-cost synthetic pr...
Antimalarial agents structurally based on novel pharmacophores, synthesized by low-cost synthetic pr...
Malaria is a major health problem in poverty-stricken regions where new antiparasitic drugs are urge...
International audienceAmodiaquine remains one of the most prescribed antimalarial 4-aminoquinoline. ...
Malaria is a major health problem in poverty-stricken regions where new antiparasitic drugs are urge...
Antimalarial agents having a novel pharmacophore of formula (I) are herein described. These polycycl...
The synthesis of imidazolidin-4-one derivatives of primaquine containing the five-membered ring at t...
Identification of new molecular scaffolds structurally unrelated to known antimalarials may represen...
Identification of new molecular scaffolds structurally unrelated to known antimalarials may represen...
The synthesis of imidazolidin-4-one derivatives of primaquine as potential antimalarial agents is de...
Identification of new molecular scaffolds structurally unrelated to known antimalarials may represen...
Imidazolidin-4-one derivatives of primaquine were synthesized as potential double prodrugs of the pa...
In order to develop new effective antimalarial agents, we have demonstrated that the replacement of ...
The increasing resistance of the malaria parasite P. falciparum to currently available drugs demand...
The synthesis of imidazolidin-4-one derivatives of primaquine as potential antimalarial agents is de...
Antimalarial agents structurally based on novel pharmacophores, synthesized by low-cost synthetic pr...
Antimalarial agents structurally based on novel pharmacophores, synthesized by low-cost synthetic pr...
Malaria is a major health problem in poverty-stricken regions where new antiparasitic drugs are urge...
International audienceAmodiaquine remains one of the most prescribed antimalarial 4-aminoquinoline. ...
Malaria is a major health problem in poverty-stricken regions where new antiparasitic drugs are urge...