We investigated the effect of modeled microgravity (MMG) on normal vascular smooth muscle cells (VSMC) and neoplastic human breast cancer cells (MCF-7). In both cell types, MMG induced partial arrest in G2M and increased p14-3-3, HSP70, HSP60 and p21 expression. Cells synchronized by 24h starvation reentered the normal cycle within 24h if released in complete medium and exposed to normal gravity, but not if exposed to MMG. Similarly, MMG prevented VSMC and MCF-7 cells from overcoming growth arrest and re-synthesizing DNA. This study shows that cells adjust their metabolic rate in response to MMG
Microgravity affects human cardiovascular function inducing heart rhythm disturbances and even cardi...
Previous expts. from flight- and ground-based model systems indicate unexpected alterations of human...
One of the hallmarks of microgravity-induced effects in several cellular models is represented by th...
We investigated the effect of modeled microgravity (MMG) on normal vascular smooth muscle cells (VSM...
AbstractWe investigated the effect of modeled microgravity (MMG) on normal vascular smooth muscle ce...
In this paper we report the behaviour of normal vascular smooth muscle cells and transformed breast ...
In this paper we report the behaviour of normal vascular smooth muscle cells and transformed breast...
Background: The impact of the absence of gravity on cancer cells is of great interest, especially to...
Astronauts are susceptible to a variety of conditions such as motion sickness, muscular atrophy, bon...
Background: In space, the reduction or loss of the gravity vector greatly affects the interaction be...
Background: In space, the reduction or loss of the gravity vector greatly affects the interaction be...
Short-term or long-term space flight induces numerous biological stressors that affect several human...
Abstract: Background: In space, the reduction or loss of the gravity vector greatly affects the int...
Exposure to outer space microgravity poses a risk for the development of various pathologies includi...
Abstract Background Gravity is omnipresent on Earth; however, humans in space, such as astronauts at...
Microgravity affects human cardiovascular function inducing heart rhythm disturbances and even cardi...
Previous expts. from flight- and ground-based model systems indicate unexpected alterations of human...
One of the hallmarks of microgravity-induced effects in several cellular models is represented by th...
We investigated the effect of modeled microgravity (MMG) on normal vascular smooth muscle cells (VSM...
AbstractWe investigated the effect of modeled microgravity (MMG) on normal vascular smooth muscle ce...
In this paper we report the behaviour of normal vascular smooth muscle cells and transformed breast ...
In this paper we report the behaviour of normal vascular smooth muscle cells and transformed breast...
Background: The impact of the absence of gravity on cancer cells is of great interest, especially to...
Astronauts are susceptible to a variety of conditions such as motion sickness, muscular atrophy, bon...
Background: In space, the reduction or loss of the gravity vector greatly affects the interaction be...
Background: In space, the reduction or loss of the gravity vector greatly affects the interaction be...
Short-term or long-term space flight induces numerous biological stressors that affect several human...
Abstract: Background: In space, the reduction or loss of the gravity vector greatly affects the int...
Exposure to outer space microgravity poses a risk for the development of various pathologies includi...
Abstract Background Gravity is omnipresent on Earth; however, humans in space, such as astronauts at...
Microgravity affects human cardiovascular function inducing heart rhythm disturbances and even cardi...
Previous expts. from flight- and ground-based model systems indicate unexpected alterations of human...
One of the hallmarks of microgravity-induced effects in several cellular models is represented by th...
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