C-type natriuretic peptide (CNP) was recently found in the myocardium, but possible insights into differences between atrium and ventricle production are so far lacking. Our aim was to evaluate, in an experimental model of pacing-induced heart failure (HF), plasma and tissue levels of CNP and mRNA expression of the peptide and of its specific receptor, NPR-B. Cardiac tissue was collected from male adult minipigs without (control, n=5) and with pacing-induced HF (n=5). Blood samples were collected at baseline and after pacing (10 min, 1, 2, 3 weeks). CNP in plasma and in cardiac extracts was determined by a radioimmunoassay, while the expression of mRNA by real time PCR. Compared to control, plasma CNP was increased after 1 week of pacing st...
Natriuretic peptides (NPs), including atrial, brain and C-type natriuretic peptides (ANP, BNP and CN...
We previously found a negative inotropic (NIR) and positive lusitropic response (LR) to C-type natri...
AbstractObjectives. The objectives of this study were 1) to define in an experimental model of heart...
C-type natriuretic peptide (CNP) was recently found in the myocardium, but possible insights into di...
AIM:The increased myocardial production and the elevated plasma concentrations of C-type natriuretic...
Purpose: Higher plasma levels and a cardiac production of C-type natriuretic peptide (CNP) were rece...
High-frequency pacing of the left ventricle (LV) free wall causes a dyssynchronous pattern of contra...
Background. C-type natriuretic peptide (CNP) was recently found in the myocardium, but possible diff...
C-type natriuretic peptide (CNP) was recently found in myocardium at the mRNA and protein levels, bu...
Purpose: It has been recently demonstrated in an animal model of heart failure (HF) that the high-fr...
Dipyridamole (DP) restores ischemic tissue blood flow stimulating angiogenesis in eNOS-dependent pat...
Background— C-type natriuretic peptide (CNP) is a vasodilator produced by the vascular endothelium. ...
After the isolation of C-type natriuretic peptide (CNP) from porcine brain tissue, both CNP and CNP ...
Plasma atrial and brain natriuretic peptide levels (ANP and BNP) are elevated in heart failure (HF) ...
Natriuretic peptides (NPs), including atrial, brain and C-type natriuretic peptides (ANP, BNP and CN...
We previously found a negative inotropic (NIR) and positive lusitropic response (LR) to C-type natri...
AbstractObjectives. The objectives of this study were 1) to define in an experimental model of heart...
C-type natriuretic peptide (CNP) was recently found in the myocardium, but possible insights into di...
AIM:The increased myocardial production and the elevated plasma concentrations of C-type natriuretic...
Purpose: Higher plasma levels and a cardiac production of C-type natriuretic peptide (CNP) were rece...
High-frequency pacing of the left ventricle (LV) free wall causes a dyssynchronous pattern of contra...
Background. C-type natriuretic peptide (CNP) was recently found in the myocardium, but possible diff...
C-type natriuretic peptide (CNP) was recently found in myocardium at the mRNA and protein levels, bu...
Purpose: It has been recently demonstrated in an animal model of heart failure (HF) that the high-fr...
Dipyridamole (DP) restores ischemic tissue blood flow stimulating angiogenesis in eNOS-dependent pat...
Background— C-type natriuretic peptide (CNP) is a vasodilator produced by the vascular endothelium. ...
After the isolation of C-type natriuretic peptide (CNP) from porcine brain tissue, both CNP and CNP ...
Plasma atrial and brain natriuretic peptide levels (ANP and BNP) are elevated in heart failure (HF) ...
Natriuretic peptides (NPs), including atrial, brain and C-type natriuretic peptides (ANP, BNP and CN...
We previously found a negative inotropic (NIR) and positive lusitropic response (LR) to C-type natri...
AbstractObjectives. The objectives of this study were 1) to define in an experimental model of heart...