Topics
inosine monophosphate dehydrogenaseBiomolecule
virusAnimal
GrapevineInsect
chemotherapyTelevision station
mercaptopurineChemical substance
6-mercaptopurineChemical substance
Chemicals that can inhibit other sensible point of purine biosynthesis than inosine monophosphate dehydrogenase are considered as potential antiviral drugs. Among them, mercaptopurine and its derivates are immunosuppressive drugs widely used in medical therapy, which mechanism of action can be partially associated to inhibition of purine biosynthesis. Aim of this research is a preliminary study regarding the antiviral action of 2-amino-6-mercaptopurine against Grapevine Leafroll-associated virus-1 and -3 in grapevine plants. The drugs seems to be effective on virus replication but any eradication of virus was registered. These findings suggest further steps of treatments and/or higher dosage of drug, making mercaptopurines interesting as gr...
Investigations were conducted into the feasibility of inhibiting proofreading exonuclease activity d...
119 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2005.Grape and its cell culture ex...
The file attached to this record is the author's final peer reviewed version. The Publisher's final ...
Thiopurine prodrugs are antiviral chemicals used in medical therapy whose mechanisms of action ar...
The ability to control plant viral disease with chemicals has great potential value for agriculture,...
The detrimental effects of virus infections on yield quantity/quality highlight the importance of vi...
To evaluate the role of purines in antiviral treatments in plants, ribavirin (RB) and tiazofurin (TZ...
Different chemotherapeutic strategies on closely correlated phytoviruses, such as Grapevine leafroll...
Many viruses within the Flavivirus genus cause significant disease in humans; however, effective ant...
The major disease targets for antiviral chemotherapy are influ-enza, rhinovirus colds and herpetic i...
Plant products have been used to treat various diseases since ancient times thanks to the many activ...
Potential antiviral agents. Studies in the synthesis of deoxy and amino sugars</p
The coronavirus pandemic (SARS CoV-2) that has existed for over a year, constantly forces scientists...
Grape seed extract (GSE) is a rich source of polyphenols, important secondary metabolites which play...
Introduction. Influenza and acute respiratory viral infection (hereinafter – ARVI) are serious disea...
Investigations were conducted into the feasibility of inhibiting proofreading exonuclease activity d...
119 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2005.Grape and its cell culture ex...
The file attached to this record is the author's final peer reviewed version. The Publisher's final ...
Thiopurine prodrugs are antiviral chemicals used in medical therapy whose mechanisms of action ar...
The ability to control plant viral disease with chemicals has great potential value for agriculture,...
The detrimental effects of virus infections on yield quantity/quality highlight the importance of vi...
To evaluate the role of purines in antiviral treatments in plants, ribavirin (RB) and tiazofurin (TZ...
Different chemotherapeutic strategies on closely correlated phytoviruses, such as Grapevine leafroll...
Many viruses within the Flavivirus genus cause significant disease in humans; however, effective ant...
The major disease targets for antiviral chemotherapy are influ-enza, rhinovirus colds and herpetic i...
Plant products have been used to treat various diseases since ancient times thanks to the many activ...
Potential antiviral agents. Studies in the synthesis of deoxy and amino sugars</p
The coronavirus pandemic (SARS CoV-2) that has existed for over a year, constantly forces scientists...
Grape seed extract (GSE) is a rich source of polyphenols, important secondary metabolites which play...
Introduction. Influenza and acute respiratory viral infection (hereinafter – ARVI) are serious disea...
Investigations were conducted into the feasibility of inhibiting proofreading exonuclease activity d...
119 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2005.Grape and its cell culture ex...
The file attached to this record is the author's final peer reviewed version. The Publisher's final ...
Add to ORKG