Autoimmune Addison’s disease (AAD) is defined as primary adrenal insufficiency due to immune-mediated destruction of the adrenal cortex. This destruction of steroid-producing cells has historically been thought of as an irreversible process, with linear progression from an ACTH-driven compensated phase to overt adrenal insufficie ncy requiring lifelong glucocorticoid replacement. However, a growing body of evidence suggests that this process may be more heterogeneous than previously thought, with potential for complete or partial recovery of glucocorticoid secretion. Although patients with persistent mineralocorticoid deficiency despite preserved or recovered glucocorticoid function are anecdotally mentioned, few well-documented cases have ...
Abstract Recent progress in the immunopathology field has greatly improved our understanding of the...
Introduction and purpose Addison's syndrome is defined as primary adrenal insufficiency, the symptom...
Background: The most common cause of primary adrenal failure (Addison’s disease) in the Western worl...
Context: The natural history of adrenal function in autoimmune Addison’s disease once diagnosed and ...
UNLABELLED: Addison's disease is a condition characterised by immune-mediated destruction of the adr...
Background: Underlying causes of adrenal insufficiency include congenital adrenal hyperplasia (CAH) ...
Autoimmune Addison's disease (AAD) is the most frequent cause of adrenocortical insufficiency. The n...
Context Contrary to current dogma, growing evidence suggests that some patients with autoimmune Addi...
Addison's disease - the traditional term for primary adrenal insufficiency (PAI) - is defined as the...
The adrenal glands are small endocrine glands located on top of each kidney, producing hormones regu...
Adrenal cortex autoantibodies (ACA) and/or 21-hydroxylase (21OHAb) are markers of autoimmune Addison...
Primary adrenal insufficiency (PAI) is a rare condition in childhood which is either inherited (most...
characterised by wasting and hyperpigmentation, and identified its cause as destruction of the adren...
Phd ThesisAutoimmune Addison’s disease (AAD) is a debilitating condition and affected patients rely ...
In the first part of this thesis we discuss a concise stepwise approach for the diagnostic evaluatio...
Abstract Recent progress in the immunopathology field has greatly improved our understanding of the...
Introduction and purpose Addison's syndrome is defined as primary adrenal insufficiency, the symptom...
Background: The most common cause of primary adrenal failure (Addison’s disease) in the Western worl...
Context: The natural history of adrenal function in autoimmune Addison’s disease once diagnosed and ...
UNLABELLED: Addison's disease is a condition characterised by immune-mediated destruction of the adr...
Background: Underlying causes of adrenal insufficiency include congenital adrenal hyperplasia (CAH) ...
Autoimmune Addison's disease (AAD) is the most frequent cause of adrenocortical insufficiency. The n...
Context Contrary to current dogma, growing evidence suggests that some patients with autoimmune Addi...
Addison's disease - the traditional term for primary adrenal insufficiency (PAI) - is defined as the...
The adrenal glands are small endocrine glands located on top of each kidney, producing hormones regu...
Adrenal cortex autoantibodies (ACA) and/or 21-hydroxylase (21OHAb) are markers of autoimmune Addison...
Primary adrenal insufficiency (PAI) is a rare condition in childhood which is either inherited (most...
characterised by wasting and hyperpigmentation, and identified its cause as destruction of the adren...
Phd ThesisAutoimmune Addison’s disease (AAD) is a debilitating condition and affected patients rely ...
In the first part of this thesis we discuss a concise stepwise approach for the diagnostic evaluatio...
Abstract Recent progress in the immunopathology field has greatly improved our understanding of the...
Introduction and purpose Addison's syndrome is defined as primary adrenal insufficiency, the symptom...
Background: The most common cause of primary adrenal failure (Addison’s disease) in the Western worl...