The response of serum transaminase levels to penicillamine and zinc treatment in Wilson's disease is poorly understood. The aim of this multicenter retrospective study was to evaluate transaminase levels after penicillamine and zinc treatment in children with Wilson's disease. One hundred and nine patients with Wilson's disease (median age at diagnosis, 7.2 years; range, 1 to 18 years), treated for at least 12 months and observed in the last 20 years at 11 Paediatric Departments were studied. Clinical, laboratory and histologic features at diagnosis and initial treatment were recorded. Efficacy parameters were normalization of serum transaminase level and improved clinical and/or laboratory signs. One hundred and two patients had clinical ...
Aims: To report on the diagnostic features, management, and clinical outcome after different treatme...
BACKGROUND: Clinical presentations of Wilson's disease (WD) in childhood ranges from asymptomatic li...
BACKGROUND: Clinical presentations of Wilson's disease (WD) in childhood ranges from asymptomatic li...
OBJECTIVES: The response of serum transaminase levels to penicillamine and zinc treatment in Wilson'...
Objectives: The response of serum transaminase levels to penicillamine and zinc treatment in Wilson'...
OBJECTIVES: The response of serum transaminase levels to penicillamine and zinc treatment in Wilson'...
Wilson's disease (WD) is characterized by a dramatic build-up of intracellular hepatic copper with s...
Objective. The physiology of iron metabolism in Wilson's disease is largely unknown, and there is a ...
Background and aims. There are certain areas of uncertainty regarding the best therapeutic approach ...
Wilson's disease (WD) is an autosomal recessive disorder characterized by excessive accumulatio...
SUMMARY Serum copper and zinc concentrations and 24 hour urinary copper and zinc excretion were dete...
Background: Wilson's disease (WD) evolves rapidly and is fatal if untreated. The treatment of WD pat...
Aims: To report on the diagnostic features, management, and clinical outcome after different treatme...
BACKGROUND: Clinical presentations of Wilson's disease (WD) in childhood ranges from asymptomatic li...
BACKGROUND: Clinical presentations of Wilson's disease (WD) in childhood ranges from asymptomatic li...
OBJECTIVES: The response of serum transaminase levels to penicillamine and zinc treatment in Wilson'...
Objectives: The response of serum transaminase levels to penicillamine and zinc treatment in Wilson'...
OBJECTIVES: The response of serum transaminase levels to penicillamine and zinc treatment in Wilson'...
Wilson's disease (WD) is characterized by a dramatic build-up of intracellular hepatic copper with s...
Objective. The physiology of iron metabolism in Wilson's disease is largely unknown, and there is a ...
Background and aims. There are certain areas of uncertainty regarding the best therapeutic approach ...
Wilson's disease (WD) is an autosomal recessive disorder characterized by excessive accumulatio...
SUMMARY Serum copper and zinc concentrations and 24 hour urinary copper and zinc excretion were dete...
Background: Wilson's disease (WD) evolves rapidly and is fatal if untreated. The treatment of WD pat...
Aims: To report on the diagnostic features, management, and clinical outcome after different treatme...
BACKGROUND: Clinical presentations of Wilson's disease (WD) in childhood ranges from asymptomatic li...
BACKGROUND: Clinical presentations of Wilson's disease (WD) in childhood ranges from asymptomatic li...