Expression of genes that are associated with lipid metabolism and inflammation in the liver, as determined by additional real-time reverse transcription polymerase chain reaction.

A) At 3 months, expression levels of fatty acid synthase (FASN) are significantly higher in male TSOD mice than in females but are significantly higher in female db/db mice than in males (one- or two-tailed t-test). B) Expression levels of carnitine palmitoyltransferase (CPT) 1A are significantly higher in 9-month-old female TSOD mice than in their male counterparts (two-tailed t-test). C-F) For expression levels of acetyl-CoA carboxylase (ACC), CD36, F4/80, and interleukin (IL)-1b, no significant sex difference is detected (one- or two-tailed t-test). (TIF)