Spatial convergence between added X- or Y- chromosomes on the human and mouse brain without total tissue volume (TTV) correction

Spatial convergence between added X- or Y- chromosomes on the human and mouse brain without total tissue volume (TTV) correction. A. Human brain regions whose volume was either increased (red) or decreased (blue) in both aneuploidy groups. B. Correlation between beta values for the XXY_H and XYY_H group across all brain regions. C. Mouse brain regions whose volume was consistently increased (red colours) or decreased (blue colours) in 95% (950/1000 splits) of the XY_M control splits in both aneuploidy groups based on bootstrap analysis. D. Correlation between beta values for a representative split (34) for XXY_M and XYY_M groups across all brain regions. All plots use the beta values for the effect of aneuploidy with total brain volume correction.