Two aromatic acid derivatives and a xanthone from <i>Hypericum hengshanense</i>

Three previously undescribed compounds including two aromatic acid derivatives (1–2), and one xanthone (3), together with ten known compounds (4–13) were isolated from the aerial part of Hypericum hengshanense. The planar structures of three new compounds were established by 1 D and 2 D NMR and MS data. And the absolute configurations of compounds 1–2 were determined by the quantum chemical ECD calculations. Compounds 1–2 showed weak cytotoxicity against Hep-2 human cancer cell lines with IC50 values of 65.1 ± 2.7 and 78.0 ± 1.0 μg/mL, respectively.