Caveolin-1 (CAV1) is implicated in the pathophysiology of diabetes and obesity. Previously, we demonstrated an association between the CAV1 rs1997623 C > A variant and metabolic syndrome (MetS). Here, we decipher the functional role of rs1997623 in CAV1 gene regulation. A cohort of 38 patients participated in this study. The quantitative MetS scores (siMS) of the participants were computed. CAV1 transcript and protein expression were tested in subcutaneous adipose tissue using RT-PCR and immunohistochemistry. Chromatin immunoprecipitation assays were performed using primary preadipocytes isolated from individuals with different CAV1 rs1997623 genotypes (AA, AC, and CC). The regulatory region flanking the variant was cloned into a luciferase...
International audienceOBJECTIVE: Defective caveolin-1 expression is now recognized as a cause of lip...
Caveolin-1 cooperates with the recently described cavin protein family to form membrane caveolae str...
Cet article contient des données supplémentaires à l'adresse suivante : http://diabetes.diabetesjour...
Caveolin-1 (CAV1) is implicated in the pathophysiology of diabetes and obesity. Previously, we demon...
Abstract Context Caveolins are 21-24 kDa integral membrane proteins that serve as scaffolds to recru...
Caveolin-1 (CAV-1) plays important roles in many aspects of cellular biology, including vesic...
Caveolin-1 (CAV1) variants have been suggested to be associated with obesity and related metabolic d...
Context and objectiveWe examined whether a prevalent caveolin-1 gene (CAV1) variant, previously rela...
Abstract Background Caveolin-1 (CAV-1) is a cholesterol-dependent essential component located in cav...
[[abstract]]OBJECTIVE: Caveolin-1 (Cav-1) is expressed abundantly in adipose tissue and involved in ...
Caveolins are 21-24 kDa integral membrane proteins that serve as scaffolds to recruit numerou...
Caveolin 1 (Cav-1) is an essential constituent of adipocyte caveolae which binds the beta subunit of...
Background: Overactivation of the aldosterone and mineralocorticoid receptor (MR) pathway is associa...
Caveolin 1 (Cav-1) is an essential constituent of adipocyte caveolae which binds the beta subunit of...
Caveolin 1 (Cav-1) is an essential constituent of adipocyte caveolae which binds the beta subunit of...
International audienceOBJECTIVE: Defective caveolin-1 expression is now recognized as a cause of lip...
Caveolin-1 cooperates with the recently described cavin protein family to form membrane caveolae str...
Cet article contient des données supplémentaires à l'adresse suivante : http://diabetes.diabetesjour...
Caveolin-1 (CAV1) is implicated in the pathophysiology of diabetes and obesity. Previously, we demon...
Abstract Context Caveolins are 21-24 kDa integral membrane proteins that serve as scaffolds to recru...
Caveolin-1 (CAV-1) plays important roles in many aspects of cellular biology, including vesic...
Caveolin-1 (CAV1) variants have been suggested to be associated with obesity and related metabolic d...
Context and objectiveWe examined whether a prevalent caveolin-1 gene (CAV1) variant, previously rela...
Abstract Background Caveolin-1 (CAV-1) is a cholesterol-dependent essential component located in cav...
[[abstract]]OBJECTIVE: Caveolin-1 (Cav-1) is expressed abundantly in adipose tissue and involved in ...
Caveolins are 21-24 kDa integral membrane proteins that serve as scaffolds to recruit numerou...
Caveolin 1 (Cav-1) is an essential constituent of adipocyte caveolae which binds the beta subunit of...
Background: Overactivation of the aldosterone and mineralocorticoid receptor (MR) pathway is associa...
Caveolin 1 (Cav-1) is an essential constituent of adipocyte caveolae which binds the beta subunit of...
Caveolin 1 (Cav-1) is an essential constituent of adipocyte caveolae which binds the beta subunit of...
International audienceOBJECTIVE: Defective caveolin-1 expression is now recognized as a cause of lip...
Caveolin-1 cooperates with the recently described cavin protein family to form membrane caveolae str...
Cet article contient des données supplémentaires à l'adresse suivante : http://diabetes.diabetesjour...