The aim of our study was to evaluate the activity of opioid receptors involved in the regulation of prolactin secretion in different kinds of hyperprolactinemic states (puerperal, idiopathic and tumoral subjects). Prolactin plasma level changes were measured after the acute administration of a met-enkephalin synthetic analogue. FK 33-824, and placebo. The prolactin-releasing effect of this drug, evident in control subjects, was blunted in patients affected by idiopathic hyperprolactinemia, and absent in puerperal and tumoral patients. These results indicate that hyperprolactinemia affects the activity of central opioid receptors, with the most evident effects in patients with highest prolactin plasma levels
Prolactin (PRL) is an anterior pituitary hormone which plays a large part in the reproductive functi...
In normal subjects, similar degrees of PRL suppression have been reported after L-dopa alone and aft...
Prolactin (PRL) is an anterior pituitary hormone which plays a large part in the reproductive functi...
The aim of our study was to evaluate the activity of opioid receptors involved in the regulation of ...
The cause of the amenorrhea that occurs in patients with hyperprolactinemia is unknown. The involvem...
The cause of the amenorrhea that occurs in patients with hyperprolactinemia is unknown. The involvem...
With the aim of examining central opioid influences on the control of luteinizing hormone (LH) secre...
The role of endogenous opiate peptides in puerperal hyperprolactinaemia, and in the control of TSH i...
We have recently shown that dermorphin (D), a new potent opioid peptide (H-Tyr-D-Ala-Phe-Gly-Tyr-Pro...
In order to investigate the opiate receptors involved in the control of anterior pituitary hormone s...
It is becoming increasingly clear that the effects of the opioids and their synthetic analogs on ant...
ecretion, we evaluated the LH response to naloxone, an opioid receptor antagonist, in patients affec...
The plasma prolactin (PRL) response to the opiate antagonist naloxone was tested in drug-free health...
Prolactin (PRL) is an anterior pituitary hormone which plays a large part in the reproductive functi...
In normal subjects, similar degrees of PRL suppression have been reported after L-dopa alone and aft...
Prolactin (PRL) is an anterior pituitary hormone which plays a large part in the reproductive functi...
The aim of our study was to evaluate the activity of opioid receptors involved in the regulation of ...
The cause of the amenorrhea that occurs in patients with hyperprolactinemia is unknown. The involvem...
The cause of the amenorrhea that occurs in patients with hyperprolactinemia is unknown. The involvem...
With the aim of examining central opioid influences on the control of luteinizing hormone (LH) secre...
The role of endogenous opiate peptides in puerperal hyperprolactinaemia, and in the control of TSH i...
We have recently shown that dermorphin (D), a new potent opioid peptide (H-Tyr-D-Ala-Phe-Gly-Tyr-Pro...
In order to investigate the opiate receptors involved in the control of anterior pituitary hormone s...
It is becoming increasingly clear that the effects of the opioids and their synthetic analogs on ant...
ecretion, we evaluated the LH response to naloxone, an opioid receptor antagonist, in patients affec...
The plasma prolactin (PRL) response to the opiate antagonist naloxone was tested in drug-free health...
Prolactin (PRL) is an anterior pituitary hormone which plays a large part in the reproductive functi...
In normal subjects, similar degrees of PRL suppression have been reported after L-dopa alone and aft...
Prolactin (PRL) is an anterior pituitary hormone which plays a large part in the reproductive functi...