Regulation of HIF-1α degradation at normoxia and hypoxia.

HIF-1: the knowns and unknowns of hypoxia sensing.

Zagórska, Anna
Dulak, Józef

January 2004

Hypoxia-inducible factor-1 (HIF-1) is a transcriptional activator that functions as a master regulat...

Control of HIF-1α Levels Potentially Promotes the Tissue Repair in Various Conditions Through Target Gene Expression

Firdaus, Riyadh
Prijanti, Ani Retno

December 2021

Hypoxia inducible factor-1 (HIF-1) is a transcription factor that plays an important role in maintai...

Expression of the Hif-1α in hyperoxic conditions (H24, 5a; H48, 5c and H72, 5e) and in normoxic conditions (H24, 5b; H48, 5d and H72, 5f).

Vinciane Rebours (464402)
Miguel Albuquerque (464403)
Alain Sauvanet (396140)
Philippe Ruszniewski (464404)
Philippe Lévy (464405)
Valérie Paradis (464406)
Pierre Bedossa (48266)
Anne Couvelard (249566)

September 2013

Hyperoxia conditions promoted a more intense expression of the hypoxia pathways.</p

Regulation of gene expression by the hypoxia-inducible factors

Fedele, A.
Whitelaw, M.
Peet, D.

January 2002

Fig 3 -

Sarah R. Poll (14237697)
Renan Martin (8376315)
Elizabeth Wohler (247160)
Elizabeth S. Partan (14237700)
Elizabeth Walek (14237703)
Shaima Salman (14237706)
Daniel Groepper (175666)
Lisa Kratz (431238)
Mirlene Cernach (14237709)
Reynaldo Jesus-Garcia (14237712)
Chad Haldeman-Englert (14237715)
Yoon Jae Choi (14237718)
Carol D. Morris (3878236)
Bernard Cohen (3296304)
Julie Hoover-Fong (3862954)
David Valle (247174)
Gregg L. Semenza (14237721)
Nara L. M. Sobreira (14237724)

December 2022

A. RNA-seq comparison of hypoxia-induced differentially expressed genes from primary fibroblasts fro...

Effect of GoF IDH1 and IDH2 variants on KDM4C and HIF-1α.

Sarah R. Poll (14237697)
Renan Martin (8376315)
Elizabeth Wohler (247160)
Elizabeth S. Partan (14237700)
Elizabeth Walek (14237703)
Shaima Salman (14237706)
Daniel Groepper (175666)
Lisa Kratz (431238)
Mirlene Cernach (14237709)
Reynaldo Jesus-Garcia (14237712)
Chad Haldeman-Englert (14237715)
Yoon Jae Choi (14237718)
Carol D. Morris (3878236)
Bernard Cohen (3296304)
Julie Hoover-Fong (3862954)
David Valle (247174)
Gregg L. Semenza (14237721)
Nara L. M. Sobreira (14237724)

December 2022

*Asterisks denote genes found mutated in probands with OD or MS in this study.</p

Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations

Sutter, Carrie Hayes
Laughner, Erik
Semenza, Gregg L.

April 2000

Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that mediates cellular and systemic hom...

HIF-1α stabilisation regulates cell area.

Melanie Vogler (434439)
Sabine Vogel (434440)
Sabine Krull (434441)
Katja Farhat (225436)
Pia Leisering (434442)
Susanne Lutz (434443)
Christina M. Wuertz (434444)
Dörthe M. Katschinski (434445)
Anke Zieseniss (434446)

July 2013

(A) Schematic drawing of HIF-1 and its regulation in normoxia and hypoxia. The stability of the H...

Hypoxia induces HIF-1α and HIF-1-target-gene expression.

Markus Wagegg (305265)
Timo Gaber (305266)
Ferenz L. Lohanatha (305269)
Martin Hahne (305271)
Cindy Strehl (305273)
Monique Fangradt (305274)
Cam Loan Tran (305275)
Kerstin Schönbeck (305276)
Paula Hoff (305277)
Andrea Ode (108604)
Carsten Perka (283464)
Georg N. Duda (108610)
Frank Buttgereit (305278)

February 2013

(a) HIF1A gene expression of human MSCs obtained by real-time PCR (n = 6; unpaired t-test)...

Hypoxic regulation of the hypoxia-inducible factor-1α (HIF-1α) transcription factor is primarily through inhibition of degradation

Carol A Hitchon (71324)
Hani S El-Gabalawy (69937)

December 2011

Copyright information:Taken from "Oxidation in rheumatoid arthritis"Arthriti...

Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1)

Greijer, A.E.
van der Groep, P.
Kemming, D.
Shvarts, A.
Semenza, G.L.
Meijer, G.J.
van de Wiel, M.A.
Belien, J.A.M.
Van Diest, P
van der Wall, E.E.

July 2005

The hypoxia-inducible factor 1 (HIF-1) plays a critical role in cellular responses to hypoxia. The a...

Mutation analysis of the HIF-1α oxygen-dependent degradation domain in invasive breast cancer

Vleugel, M.M.
Greijer, A.E.
Wall, E. van der
Diest, P.J. van

January 2005

Hypoxia inducible factor-1 (HIF-1) is an important transcription factor that stimulates tumor growth...

Influence of HIF–1α knockdown by siRNA in ASCs under hypoxia (A) The relative mRNA expression levels of HIF–1α in ASCs after transfection for 48 h under hypoxia. HIF–1α level was suppressed significantly compared with that in the control. (B) The relative mRNA expression levels of FGF–2 in ASCs after transfection for 48 h under hypoxia. FGF–2 level was suppressed significantly compared with that in the control. (C) The relative mRNA expression levels of VEGF in ASCs after transfection for 48 h under hypoxia. VEGF level was suppressed significantly compared with that in the control. Data are the means ± SD. *p < 0.05. (D) Expression of HIF–1α was inhibited by siRNA using western blotting.

Natsuko Kakudo (777452)
Naoki Morimoto (148785)
Takeshi Ogawa (739661)
Shigeru Taketani (78342)
Kenji Kusumoto (777454)

October 2015

Influence of HIF–1α knockdown by siRNA in ASCs under hypoxia (A) The relative mRNA expression lev...

MINIREVIEW Hypoxia-Inducible Factor-1 (HIF-1)

Qingdong Ke
Max Costa

January 2006

Adaptation to low oxygen tension (hypoxia) in cells and tissues leads to the transcriptional inducti...

Analysis of HIF-1alpha degradation and function

André, Helder

December 2005

HIF-1 is a heterodimeric complex of two bHLH/PAS transcription factors, HIF- 1alpha and ANRT. In con...

HIF-1: the knowns and unknowns of hypoxia sensing.

Zagórska, Anna
Dulak, Józef

January 2004

Hypoxia-inducible factor-1 (HIF-1) is a transcriptional activator that functions as a master regulat...

Control of HIF-1α Levels Potentially Promotes the Tissue Repair in Various Conditions Through Target Gene Expression

Firdaus, Riyadh
Prijanti, Ani Retno

December 2021

Hypoxia inducible factor-1 (HIF-1) is a transcription factor that plays an important role in maintai...

Expression of the Hif-1α in hyperoxic conditions (H24, 5a; H48, 5c and H72, 5e) and in normoxic conditions (H24, 5b; H48, 5d and H72, 5f).

Vinciane Rebours (464402)
Miguel Albuquerque (464403)
Alain Sauvanet (396140)
Philippe Ruszniewski (464404)
Philippe Lévy (464405)
Valérie Paradis (464406)
Pierre Bedossa (48266)
Anne Couvelard (249566)

September 2013

Hyperoxia conditions promoted a more intense expression of the hypoxia pathways.</p

Regulation of gene expression by the hypoxia-inducible factors

Fedele, A.
Whitelaw, M.
Peet, D.

January 2002

Fig 3 -

Sarah R. Poll (14237697)
Renan Martin (8376315)
Elizabeth Wohler (247160)
Elizabeth S. Partan (14237700)
Elizabeth Walek (14237703)
Shaima Salman (14237706)
Daniel Groepper (175666)
Lisa Kratz (431238)
Mirlene Cernach (14237709)
Reynaldo Jesus-Garcia (14237712)
Chad Haldeman-Englert (14237715)
Yoon Jae Choi (14237718)
Carol D. Morris (3878236)
Bernard Cohen (3296304)
Julie Hoover-Fong (3862954)
David Valle (247174)
Gregg L. Semenza (14237721)
Nara L. M. Sobreira (14237724)

December 2022

A. RNA-seq comparison of hypoxia-induced differentially expressed genes from primary fibroblasts fro...

Effect of GoF IDH1 and IDH2 variants on KDM4C and HIF-1α.

Sarah R. Poll (14237697)
Renan Martin (8376315)
Elizabeth Wohler (247160)
Elizabeth S. Partan (14237700)
Elizabeth Walek (14237703)
Shaima Salman (14237706)
Daniel Groepper (175666)
Lisa Kratz (431238)
Mirlene Cernach (14237709)
Reynaldo Jesus-Garcia (14237712)
Chad Haldeman-Englert (14237715)
Yoon Jae Choi (14237718)
Carol D. Morris (3878236)
Bernard Cohen (3296304)
Julie Hoover-Fong (3862954)
David Valle (247174)
Gregg L. Semenza (14237721)
Nara L. M. Sobreira (14237724)

December 2022

*Asterisks denote genes found mutated in probands with OD or MS in this study.</p

Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations

Sutter, Carrie Hayes
Laughner, Erik
Semenza, Gregg L.

April 2000

Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that mediates cellular and systemic hom...

HIF-1α stabilisation regulates cell area.

Melanie Vogler (434439)
Sabine Vogel (434440)
Sabine Krull (434441)
Katja Farhat (225436)
Pia Leisering (434442)
Susanne Lutz (434443)
Christina M. Wuertz (434444)
Dörthe M. Katschinski (434445)
Anke Zieseniss (434446)

July 2013

(A) Schematic drawing of HIF-1 and its regulation in normoxia and hypoxia. The stability of the H...

Hypoxia induces HIF-1α and HIF-1-target-gene expression.

Markus Wagegg (305265)
Timo Gaber (305266)
Ferenz L. Lohanatha (305269)
Martin Hahne (305271)
Cindy Strehl (305273)
Monique Fangradt (305274)
Cam Loan Tran (305275)
Kerstin Schönbeck (305276)
Paula Hoff (305277)
Andrea Ode (108604)
Carsten Perka (283464)
Georg N. Duda (108610)
Frank Buttgereit (305278)

February 2013

(a) HIF1A gene expression of human MSCs obtained by real-time PCR (n = 6; unpaired t-test)...

Hypoxic regulation of the hypoxia-inducible factor-1α (HIF-1α) transcription factor is primarily through inhibition of degradation

Carol A Hitchon (71324)
Hani S El-Gabalawy (69937)

December 2011

Copyright information:Taken from "Oxidation in rheumatoid arthritis"Arthriti...

Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1)

Greijer, A.E.
van der Groep, P.
Kemming, D.
Shvarts, A.
Semenza, G.L.
Meijer, G.J.
van de Wiel, M.A.
Belien, J.A.M.
Van Diest, P
van der Wall, E.E.

July 2005

The hypoxia-inducible factor 1 (HIF-1) plays a critical role in cellular responses to hypoxia. The a...

Mutation analysis of the HIF-1α oxygen-dependent degradation domain in invasive breast cancer

Vleugel, M.M.
Greijer, A.E.
Wall, E. van der
Diest, P.J. van

January 2005

Hypoxia inducible factor-1 (HIF-1) is an important transcription factor that stimulates tumor growth...

Influence of HIF–1α knockdown by siRNA in ASCs under hypoxia (A) The relative mRNA expression levels of HIF–1α in ASCs after transfection for 48 h under hypoxia. HIF–1α level was suppressed significantly compared with that in the control. (B) The relative mRNA expression levels of FGF–2 in ASCs after transfection for 48 h under hypoxia. FGF–2 level was suppressed significantly compared with that in the control. (C) The relative mRNA expression levels of VEGF in ASCs after transfection for 48 h under hypoxia. VEGF level was suppressed significantly compared with that in the control. Data are the means ± SD. *p < 0.05. (D) Expression of HIF–1α was inhibited by siRNA using western blotting.

Natsuko Kakudo (777452)
Naoki Morimoto (148785)
Takeshi Ogawa (739661)
Shigeru Taketani (78342)
Kenji Kusumoto (777454)

October 2015

Influence of HIF–1α knockdown by siRNA in ASCs under hypoxia (A) The relative mRNA expression lev...

MINIREVIEW Hypoxia-Inducible Factor-1 (HIF-1)

Qingdong Ke
Max Costa

January 2006

Adaptation to low oxygen tension (hypoxia) in cells and tissues leads to the transcriptional inducti...

Analysis of HIF-1alpha degradation and function

André, Helder

December 2005

HIF-1 is a heterodimeric complex of two bHLH/PAS transcription factors, HIF- 1alpha and ANRT. In con...

HIF-1: the knowns and unknowns of hypoxia sensing.

Zagórska, Anna
Dulak, Józef

January 2004

Hypoxia-inducible factor-1 (HIF-1) is a transcriptional activator that functions as a master regulat...

Control of HIF-1α Levels Potentially Promotes the Tissue Repair in Various Conditions Through Target Gene Expression

Firdaus, Riyadh
Prijanti, Ani Retno

December 2021

Hypoxia inducible factor-1 (HIF-1) is a transcription factor that plays an important role in maintai...

Expression of the Hif-1α in hyperoxic conditions (H24, 5a; H48, 5c and H72, 5e) and in normoxic conditions (H24, 5b; H48, 5d and H72, 5f).

Vinciane Rebours (464402)
Miguel Albuquerque (464403)
Alain Sauvanet (396140)
Philippe Ruszniewski (464404)
Philippe Lévy (464405)
Valérie Paradis (464406)
Pierre Bedossa (48266)
Anne Couvelard (249566)

September 2013

Hyperoxia conditions promoted a more intense expression of the hypoxia pathways.</p

Regulation of HIF-1α degradation at normoxia and hypoxia.

Abstract

Extracted data

Regulation of HIF-1α degradation at normoxia and hypoxia.

Abstract

Extracted data

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