Genome-wide analysis of core promoter elements from conserved human and mouse orthologous pairs
- Jin, Victor X.
- Singer, Gregory AC
- Agosto-Pérez, Francisco J.
- Liyanarachchi, Sandya
- Davuluri, Ramana V.
Publication date
January 2006
DOI Publisher
Springer Science and Business Media LLCAbstract
The canonical core promoter elements consist of the TATA box, initiator (Inr), downstream core promoter element (DPE), TFIIB recognition element (BRE) and the newly-discovered motif 10 element (MTE). The motifs for these core promoter elements are highly degenerate, which tends to lead to a high false discovery rate when attempting to detect them in promoter sequences
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