Maintenance of picobirnavirus (PBV) infection in an adult orangutan (Pongo pygmaeus) and genetic diversity of excreted viral strains during a three-year period
- Masachessi, Gisela
- Ganesh, Balasubramanian
- Martinez, Laura Cecilia
- Giordano, Miguel Oscar
- Barril, Patricia Angelica
- Isa, Maria Beatriz
- Paván, Giorgio V.
- Mateos, Carlos Andrés
- Nates, Silvia Viviana
DOIAbstract
The present work provide data about the maintenance of picobirnavirus (PBV) infection during adulthood in a mammalian host. For this purpose PBV infection was studied in an adult orangutan (. Pongo pygmaeus) by PAGE/SS, RT-PCR and nucleotide sequencing. PBV infection in the animal was asymptomatic and was characterized by interspaced silent and high/ low active viral excretion periods. The PBV strains excreted by the studied individual were identified as genogroup I and revealed a nucleotide identity among them of 64-81%.The results obtained allowed to arrive to a deeper understanding of the natural history of PBV infection, which seems to be characterized by new-born, juvenile and adult asymptomatic hosts which persistently excrete closely...
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