Vestibular schwannomas are benign nerve sheath tumours that arise on the vestibulocochlear nerves. Vestibular schwannomas are known to occur in the context of tumour predisposition syndromes NF2-related and LZTR1-related schwannomatosis. However, the majority of vestibular schwannomas present sporadically without identification of germline pathogenic variants.To identify novel genetic associations with risk of vestibular schwannoma development, we conducted a genome-wide association study in a cohort of 911 sporadic vestibular schwannoma cases collated from the neurofibromatosis type 2 genetic testing service in the North West of England, UK and 5,500 control samples from the UK Biobank resource. One risk locus reached genome-wide significa...
NF2 is caused by mutations of the NF2 gene. The NF2 gene was mapped to the long arm of chromosome 22...
Introduction Vestibular schwannoma (VS) is a benign intracranial tumor in which the underlying genet...
Vestibular schwannoma occurs both as a sporadic tumour and In the dominantly inherited familial canc...
Background: Unilateral sporadic vestibular schwannomas (USVS) are caused by inactivating somatic mut...
Background: Vestibular schwannoma (VS) is a benign intracranial neoplasm associated with reduced qua...
Vestibular schwannomas are benign neoplasms that arise from the vestibular nerve. The hallmark of th...
Neurofibromatosis type 2 (NF2) is an autosomal dominant disorder with the clinical hallmark of bilat...
Background: Neurofibromatosis Type 2 (NF2) is a dominantly inherited tumour syndrome with a phenotyp...
Background: Mutations in the neurofibromatosis type 2 (NF2) tumor-suppressor gene have been identifi...
BACKGROUND: Mutations in the neurofibromatosis type 2 (NF2) tumor-suppressor gene have been identifi...
Background: Schwannomas are the most common neurofibromatosis type 2 (NF2)-associated tumors with si...
SIGLEAvailable from British Library Document Supply Centre-DSC:DXN011098 / BLDSC - British Library D...
Objective: In order to identify genetic variants associated with vestibular neuritis, a common cause...
Vestibular schwannomas (VS) are known to carry mutations on the neurofibromatosis type 2 (NF2) tumor...
Aim: Neurofibromatosis type 2 (NF2)-associated vestibular schwannomas have variable size at presenta...
NF2 is caused by mutations of the NF2 gene. The NF2 gene was mapped to the long arm of chromosome 22...
Introduction Vestibular schwannoma (VS) is a benign intracranial tumor in which the underlying genet...
Vestibular schwannoma occurs both as a sporadic tumour and In the dominantly inherited familial canc...
Background: Unilateral sporadic vestibular schwannomas (USVS) are caused by inactivating somatic mut...
Background: Vestibular schwannoma (VS) is a benign intracranial neoplasm associated with reduced qua...
Vestibular schwannomas are benign neoplasms that arise from the vestibular nerve. The hallmark of th...
Neurofibromatosis type 2 (NF2) is an autosomal dominant disorder with the clinical hallmark of bilat...
Background: Neurofibromatosis Type 2 (NF2) is a dominantly inherited tumour syndrome with a phenotyp...
Background: Mutations in the neurofibromatosis type 2 (NF2) tumor-suppressor gene have been identifi...
BACKGROUND: Mutations in the neurofibromatosis type 2 (NF2) tumor-suppressor gene have been identifi...
Background: Schwannomas are the most common neurofibromatosis type 2 (NF2)-associated tumors with si...
SIGLEAvailable from British Library Document Supply Centre-DSC:DXN011098 / BLDSC - British Library D...
Objective: In order to identify genetic variants associated with vestibular neuritis, a common cause...
Vestibular schwannomas (VS) are known to carry mutations on the neurofibromatosis type 2 (NF2) tumor...
Aim: Neurofibromatosis type 2 (NF2)-associated vestibular schwannomas have variable size at presenta...
NF2 is caused by mutations of the NF2 gene. The NF2 gene was mapped to the long arm of chromosome 22...
Introduction Vestibular schwannoma (VS) is a benign intracranial tumor in which the underlying genet...
Vestibular schwannoma occurs both as a sporadic tumour and In the dominantly inherited familial canc...