(A-C) Late 3rd instar wing discs labelled with PHN. Anterior is to the left. Compared to the control nub>p35 (A), a massive increase of F-actin filaments was observed in the overgrown wing pouch area of the nub>hid-p35 discs (B, arrows). Such F-actin accumulation and tissue overgrowth were suppressed by a knockdown of LIMK1 with RNAi (C). (TIF)</p
<p>Confocal optical sections acquired apically (A–B), in the middle (C–D) and at the basal side of t...
LIM kinases 1 and 2 (LIMK1/2) are centrally positioned regulators of actin cytoskeleton dynamics. Us...
Stress-induced cell death, mainly apoptosis, and its subsequent tissue repair is interlinked althoug...
(A-J’) Late 3rd instar wing discs with 48-hour old mosaic clones positively marked by GFP. Phalloidi...
(A, A’) Apical side images of a late 3rd instar wing discs with 48-hour old mosaic clones, positivel...
(A-E’) Late 3rd instar eye discs labelled with phalloidin (PHN), a marker of F-actin. A’, B’ and C’ ...
(A-D”) Late 3rd instar eye discs labelled with PHN (magenta in A-D and grey in A’-D’) and MMP1 (gree...
Late 3rd instar wing discs with 48-hour old mosaic clones positively marked by GFP. PHN (magenta in ...
(A) A schematic representation of the AiP-dependent overgrowth assay. ey-GAL4 is expressed in the de...
(A-F’) Late 3rd instar wing discs with 48-hour old mosaic clones positively marked by GFP. MMP1 (mag...
(A-F’) Late 3rd instar wing discs with 48-hour old mosaic clones positively marked by GFP. Dihydroet...
A late 3rd instar ey>hid-p35 disc labelled with PHN (magenta in A, B and grey in A’, B’) and the cle...
The Hippo tumour suppressor pathway is a conserved signalling pathway that controls organ size. The ...
The Lim-kinase (LIMK) proteins are important for the regulation of the actin cytoskeleton, in partic...
<p>Confocal optical sections were acquired apically (A–B), in the middle (C–D) and on the basal side...
<p>Confocal optical sections acquired apically (A–B), in the middle (C–D) and at the basal side of t...
LIM kinases 1 and 2 (LIMK1/2) are centrally positioned regulators of actin cytoskeleton dynamics. Us...
Stress-induced cell death, mainly apoptosis, and its subsequent tissue repair is interlinked althoug...
(A-J’) Late 3rd instar wing discs with 48-hour old mosaic clones positively marked by GFP. Phalloidi...
(A, A’) Apical side images of a late 3rd instar wing discs with 48-hour old mosaic clones, positivel...
(A-E’) Late 3rd instar eye discs labelled with phalloidin (PHN), a marker of F-actin. A’, B’ and C’ ...
(A-D”) Late 3rd instar eye discs labelled with PHN (magenta in A-D and grey in A’-D’) and MMP1 (gree...
Late 3rd instar wing discs with 48-hour old mosaic clones positively marked by GFP. PHN (magenta in ...
(A) A schematic representation of the AiP-dependent overgrowth assay. ey-GAL4 is expressed in the de...
(A-F’) Late 3rd instar wing discs with 48-hour old mosaic clones positively marked by GFP. MMP1 (mag...
(A-F’) Late 3rd instar wing discs with 48-hour old mosaic clones positively marked by GFP. Dihydroet...
A late 3rd instar ey>hid-p35 disc labelled with PHN (magenta in A, B and grey in A’, B’) and the cle...
The Hippo tumour suppressor pathway is a conserved signalling pathway that controls organ size. The ...
The Lim-kinase (LIMK) proteins are important for the regulation of the actin cytoskeleton, in partic...
<p>Confocal optical sections were acquired apically (A–B), in the middle (C–D) and on the basal side...
<p>Confocal optical sections acquired apically (A–B), in the middle (C–D) and at the basal side of t...
LIM kinases 1 and 2 (LIMK1/2) are centrally positioned regulators of actin cytoskeleton dynamics. Us...
Stress-induced cell death, mainly apoptosis, and its subsequent tissue repair is interlinked althoug...