Model for how FABP4 functions as an attractor molecule for the terminally differentiated state.
- Zahra Bahrami-Nejad (14216460)
- Zhi-Bo Zhang (14216463)
- Stefan Tholen (2618575)
- Sanjeev Sharma (1762987)
- Atefeh Rabiee (8672796)
- Michael L. Zhao (14216466)
- Fredric B. Kraemer (14216469)
- Mary N. Teruel (14216472)
Publication date
December 2022
DOI Publisher
Public Library of Science (PLoS)Abstract
When preadipocytes are stimulated to differentiate, engagement of the CEBPA-PPARG feedback loop allows the cells to reach an intermediate transition state. The cells can only reach the terminally differentiated final adipocyte state if the FABP4-PPARG feedback also engages.</p
Add to ORKG