NK cells are the most potent effectors against different tumors in vitro. However, their efficacy in vivo is compromised by suppressive signals delivered by tumor or tumor-associated cells. This study unravels the molecular mechanisms by which melanomas disarm NK cells and offers clues to revert such inhibitory effect
Metastatic disease is a major cause of death for patients with melanoma. Melanoma cells can become m...
Tumor cell plasticity is a major obstacle for the cure of malignancies as it makes tumor cells highl...
Natural killer cells are innate lymphocytes with the ability to lyse tumour cells depending on the b...
International audiencePurpose: Immunotherapy is an alternative for metastatic melanoma patients resi...
BACKGROUND: Despite Natural Killer (NK) cells were originally defined as effectors of spontaneous cy...
International audienceMelanomas are aggressive skin tumors characterized by high metastatic potentia...
Melanomas are aggressive skin tumors characterized by high metastatic potential. Immunotherapy is a ...
Natural killer (NK) receptor signaling can lead to reduced cytotoxicity by NK cells and cytolytic T ...
Melanomas are aggressive skin tumors characterized by high metastatic potential. Immunotherapy is a ...
<p><b>A:</b> Melanoma cell expression of molecules able to trigger NK cell activity. Representative ...
During the past few years, a number of studies reported that different melanoma cell lines could be ...
Natural killer (NK) cells participate in the early immune response against melanoma and also contrib...
Natural killer (NK) cells belong to the family of innate immune cells with the capacity to recognize...
Although natural killer (NK) cells play an important antitumor role, melanoma cells may affect th...
Natural killer (NK) cells play a pivotal role in cancer immunotherapy due to their innate ability to...
Metastatic disease is a major cause of death for patients with melanoma. Melanoma cells can become m...
Tumor cell plasticity is a major obstacle for the cure of malignancies as it makes tumor cells highl...
Natural killer cells are innate lymphocytes with the ability to lyse tumour cells depending on the b...
International audiencePurpose: Immunotherapy is an alternative for metastatic melanoma patients resi...
BACKGROUND: Despite Natural Killer (NK) cells were originally defined as effectors of spontaneous cy...
International audienceMelanomas are aggressive skin tumors characterized by high metastatic potentia...
Melanomas are aggressive skin tumors characterized by high metastatic potential. Immunotherapy is a ...
Natural killer (NK) receptor signaling can lead to reduced cytotoxicity by NK cells and cytolytic T ...
Melanomas are aggressive skin tumors characterized by high metastatic potential. Immunotherapy is a ...
<p><b>A:</b> Melanoma cell expression of molecules able to trigger NK cell activity. Representative ...
During the past few years, a number of studies reported that different melanoma cell lines could be ...
Natural killer (NK) cells participate in the early immune response against melanoma and also contrib...
Natural killer (NK) cells belong to the family of innate immune cells with the capacity to recognize...
Although natural killer (NK) cells play an important antitumor role, melanoma cells may affect th...
Natural killer (NK) cells play a pivotal role in cancer immunotherapy due to their innate ability to...
Metastatic disease is a major cause of death for patients with melanoma. Melanoma cells can become m...
Tumor cell plasticity is a major obstacle for the cure of malignancies as it makes tumor cells highl...
Natural killer cells are innate lymphocytes with the ability to lyse tumour cells depending on the b...