Background and Objectives: Clinically used concentrations of sevoflurane, an inhaled anesthetic, have been reported to significantly inhibit tumor growth. We investigated the effects of sevoflurane on sphere formation and the proliferation of human glioblastoma stem cells (GSCs) to determine whether sevoflurane exerts short- and long-term effects on human tumor cells. Materials and Methods: High-grade patient-derived GSCs (MD13 and Me83) were exposed to 2% sevoflurane. To evaluate the effect of sevoflurane on viability, proliferation, and stemness, we performed a caspase-3/7 essay, cell proliferation assay, and limiting dilution sphere formation assays. The expression of CD44, a cell surface marker of cancer stem-like cells in epithelial tu...
Background. Osteosarcoma is one of the most prominent bone cancers which has a predominant occurrenc...
Numerous animal studies have demonstrated that commonly used general anesthetics may result in cogni...
Aims: In this study, the effect of DNA damage in the course of sevoflurane anesthesia along with rem...
BACKGROUND:With more than 18 million annual new cases, cancer belongs to the major challenges of mod...
Background: Conventional animal models used in corresponding basic studies are distinct from humans ...
Abstract Background Inhalation of sevoflurane can induce neuronal apoptosis, cognitive impairment an...
Purpose: To determine the effects of sevoflurane on NPC-039 nasopharyngeal carcinoma cells.Methods: ...
Le Wang, Tiao Wang, Jia-Qi Gu, Hui-Bin Su Department of Anesthesiology, The Affiliated Suzhou Hospi...
Sevoflurane was frequently used as a volatile anesthetic in cancer surgery. However, the potential m...
Perioperative neurocognitive disorders are frequently observed in postoperative patients and previou...
Objective Previous studies suggested that sevoflurane exerts anti-proliferative, anti-migratory, and...
Background: Sevoflurane exposure during the early postnatal period causes neuroinflammation and neur...
BACKGROUND: The effect of sevoflurane on the neuroregenerative potential after neuronal injury is un...
Sevoflurane is the most commonly used volatile anesthetic during pregnancy. The viability of neural ...
ABSTRACT Background: We hypothesized that isoflurane has a greater potency to induce neurodegenerati...
Background. Osteosarcoma is one of the most prominent bone cancers which has a predominant occurrenc...
Numerous animal studies have demonstrated that commonly used general anesthetics may result in cogni...
Aims: In this study, the effect of DNA damage in the course of sevoflurane anesthesia along with rem...
BACKGROUND:With more than 18 million annual new cases, cancer belongs to the major challenges of mod...
Background: Conventional animal models used in corresponding basic studies are distinct from humans ...
Abstract Background Inhalation of sevoflurane can induce neuronal apoptosis, cognitive impairment an...
Purpose: To determine the effects of sevoflurane on NPC-039 nasopharyngeal carcinoma cells.Methods: ...
Le Wang, Tiao Wang, Jia-Qi Gu, Hui-Bin Su Department of Anesthesiology, The Affiliated Suzhou Hospi...
Sevoflurane was frequently used as a volatile anesthetic in cancer surgery. However, the potential m...
Perioperative neurocognitive disorders are frequently observed in postoperative patients and previou...
Objective Previous studies suggested that sevoflurane exerts anti-proliferative, anti-migratory, and...
Background: Sevoflurane exposure during the early postnatal period causes neuroinflammation and neur...
BACKGROUND: The effect of sevoflurane on the neuroregenerative potential after neuronal injury is un...
Sevoflurane is the most commonly used volatile anesthetic during pregnancy. The viability of neural ...
ABSTRACT Background: We hypothesized that isoflurane has a greater potency to induce neurodegenerati...
Background. Osteosarcoma is one of the most prominent bone cancers which has a predominant occurrenc...
Numerous animal studies have demonstrated that commonly used general anesthetics may result in cogni...
Aims: In this study, the effect of DNA damage in the course of sevoflurane anesthesia along with rem...