Keratinocyte carcinomas are among the most prevalent malignancies worldwide. Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC) are the two cancers recognized as keratinocyte carcinomas. The standard of care for treating these cancers includes surgery and ablative therapies. However, in recent years, targeted therapies (e.g., cetuximab for cSCC and vismodegib/sonidegib for BCC) have been used to treat advanced disease as well as immunotherapy (e.g., cemiplimab). These treatments are expensive and have significant toxicities with objective response rates approaching ~50–65%. Hence, there is a need to dissect the molecular pathogenesis of these cancers to identify novel biomarkers and therapeutic targets to improve diseas...
Cancer-testis (CT) antigens comprise families of tumor-associated antigens that are immunogenic in p...
Increasing evidence has revealed that the chemokines CXCL9, CXCL10, CXCL11, and their common recepto...
Cancer testis antigens (CTA) are a large family of tumor-associated antigens expressed in human tumo...
Contains fulltext : 19267_diffexged.pdf (publisher's version ) (Open Access)Human ...
Purpose of the study: to analyze characteristics of cancer-testis antigens (Ctas) as potential bioma...
The identification of cancer-specific biomolecules is of fundamental importance to the development o...
Cutaneous squamous cell carcinoma (cSCC) represents 20% of all skin cancers. Although primary cSCCs ...
Carcinoma in situ testis (CIS), also known as intratubular germ cell neoplasia (ITGCN), is a pre-inv...
Breast cancer remains one of the leading causes of death among women across the world. The last few ...
Background: Cutaneous squamous cell carcinoma (SCC) is the second most common cancer to affect popul...
Cancer/testis antigens (CTAs) are a kind of antigens that their expression mostly is restricted in t...
Background: The expression of human germline genes is restricted to the germ cells of the gonads, wh...
Using high-density oligonucleotide arrays, we measured expression of >12,000 genes in surgical excis...
Cancer cells have been found to frequently express genes that are normally restricted to the testis,...
Keratinocyte carcinomas (KC) are the most commonly diagnosed malignancies. The process of KC tumorig...
Cancer-testis (CT) antigens comprise families of tumor-associated antigens that are immunogenic in p...
Increasing evidence has revealed that the chemokines CXCL9, CXCL10, CXCL11, and their common recepto...
Cancer testis antigens (CTA) are a large family of tumor-associated antigens expressed in human tumo...
Contains fulltext : 19267_diffexged.pdf (publisher's version ) (Open Access)Human ...
Purpose of the study: to analyze characteristics of cancer-testis antigens (Ctas) as potential bioma...
The identification of cancer-specific biomolecules is of fundamental importance to the development o...
Cutaneous squamous cell carcinoma (cSCC) represents 20% of all skin cancers. Although primary cSCCs ...
Carcinoma in situ testis (CIS), also known as intratubular germ cell neoplasia (ITGCN), is a pre-inv...
Breast cancer remains one of the leading causes of death among women across the world. The last few ...
Background: Cutaneous squamous cell carcinoma (SCC) is the second most common cancer to affect popul...
Cancer/testis antigens (CTAs) are a kind of antigens that their expression mostly is restricted in t...
Background: The expression of human germline genes is restricted to the germ cells of the gonads, wh...
Using high-density oligonucleotide arrays, we measured expression of >12,000 genes in surgical excis...
Cancer cells have been found to frequently express genes that are normally restricted to the testis,...
Keratinocyte carcinomas (KC) are the most commonly diagnosed malignancies. The process of KC tumorig...
Cancer-testis (CT) antigens comprise families of tumor-associated antigens that are immunogenic in p...
Increasing evidence has revealed that the chemokines CXCL9, CXCL10, CXCL11, and their common recepto...
Cancer testis antigens (CTA) are a large family of tumor-associated antigens expressed in human tumo...