We evaluated whether the short-term use of dexmedetomidine and propofol may attenuate inflammatory response and improve lung morphofunction in experimental acute lung injury (ALI). Thirty-six Wistar rats were randomly divided into five groups. Control (C) and ALI animals received sterile saline solution and Escherichia coli lipopolysaccharide by intraperitoneal injection respectively. After 24h, ALI animals were randomly treated with dexmedetomidine, propofol, or thiopental sodium for 1h. Propofol reduced static lung elastance and resistive pressure and was associated with less alveolar collapse compared to thiopental sodium and dexmedetomidine. Dexmedetomidine improved oxygenation, but did not modify lung mechanics or histology. Propofol w...
Mechanical ventilation (MV) may lead to ventilator-induced lung injury (VILI). Previous research has...
Background: Surgery and diseases modify inflammatory responses and the immune system. Anesthetic age...
Abstract Purpose: To investigate the effect of dexmedetomidine (Dex) in a rat ex vivo lung model of...
AbstractWe evaluated whether the short-term use of dexmedetomidine and propofol may attenuate inflam...
AbstractWe evaluated whether the short-term use of dexmedetomidine and propofol may attenuate inflam...
The aim of this study was to investigate the effect of propofol pretreatment on lipopolysaccharide (...
Background: It has been suggested that propofol with ethylenediaminetetraacetic acid (EDTA) can modu...
Objective: Pulmonary complications are important sepsis (such as ARDS, diffuse pneumonia). Acute res...
Background: We assessed the effects of dexmedetomidine in a rat model of ?-naphthylthiourea (ANTU)-i...
We investigated the effect of propofol (Prop) administration (10 mg kg-1 h-1, intr...
We investigated the effect of propofol (Prop) administration (10 mg kg-1 h-1, intravenously) ...
Intravenous lipopolysaccharide (LPS) leads to acute lung injury (ALI) in rats. The purpose of this s...
BACKGROUND: Administering anesthetics to the obese population requires caution because of a vari...
WOS: 000310450300064PubMed: 22445456Background: We assessed the effects of dexmedetomidine in a rat ...
Abstract Purpose: To investigate the effects of propofol pretreatment on lung morphology and heme ...
Mechanical ventilation (MV) may lead to ventilator-induced lung injury (VILI). Previous research has...
Background: Surgery and diseases modify inflammatory responses and the immune system. Anesthetic age...
Abstract Purpose: To investigate the effect of dexmedetomidine (Dex) in a rat ex vivo lung model of...
AbstractWe evaluated whether the short-term use of dexmedetomidine and propofol may attenuate inflam...
AbstractWe evaluated whether the short-term use of dexmedetomidine and propofol may attenuate inflam...
The aim of this study was to investigate the effect of propofol pretreatment on lipopolysaccharide (...
Background: It has been suggested that propofol with ethylenediaminetetraacetic acid (EDTA) can modu...
Objective: Pulmonary complications are important sepsis (such as ARDS, diffuse pneumonia). Acute res...
Background: We assessed the effects of dexmedetomidine in a rat model of ?-naphthylthiourea (ANTU)-i...
We investigated the effect of propofol (Prop) administration (10 mg kg-1 h-1, intr...
We investigated the effect of propofol (Prop) administration (10 mg kg-1 h-1, intravenously) ...
Intravenous lipopolysaccharide (LPS) leads to acute lung injury (ALI) in rats. The purpose of this s...
BACKGROUND: Administering anesthetics to the obese population requires caution because of a vari...
WOS: 000310450300064PubMed: 22445456Background: We assessed the effects of dexmedetomidine in a rat ...
Abstract Purpose: To investigate the effects of propofol pretreatment on lung morphology and heme ...
Mechanical ventilation (MV) may lead to ventilator-induced lung injury (VILI). Previous research has...
Background: Surgery and diseases modify inflammatory responses and the immune system. Anesthetic age...
Abstract Purpose: To investigate the effect of dexmedetomidine (Dex) in a rat ex vivo lung model of...