Chronic respiratory diseases, such as asthma and chronic obstructive pulmonary disease, affect millions of patients worldwide. New therapeutic approaches to these conditions are urgently needed since current treatment options provide only symptomatic relief. Transient receptor potential (TRP) ion channels are emerging molecular target candidates for the development of novel, disease-modifying drugs addressing airway diseases
More than 30 different Transient Receptor Potential channels (TRP) have been identified in mammals a...
Abstract: There is rapidly growing evidence indicating multiple and important roles of Ca2+-permeabl...
Abstract. Ca2+ channel antagonists acting on electrically-excitable cells have proved to be valuable...
Novel effective therapeutic agents are actively sought for the treatment of a broad spectrum of resp...
Cation channels are of fundamental importance in regulating the function of airway smooth cells espe...
The lungs are essential for gas exchange and serve as the gateways of our body to the external envir...
Transient Receptor Potential Ankyrin 1 (TRPA1) ion channel is expressed abundantly on the C fibers t...
AbstractTransient receptor potential vanilloid type channels (TRPVs) are expressed in several cell t...
Although the TRPC members of the mammalian transient receptor potential TRP cation channel family we...
The mammalian transient receptor potential (TRP) superfamily consists of 28 mammalian TRP cation cha...
© 2015, National Research Council of Canada. All rights reserved. Airway smooth muscle (ASM) contrac...
Transient receptor potential (TRP) channels are a family of functionally diverse and widely expresse...
Cough is the most common reason for patients to visit a primary care physician, yet it remains an un...
The year 2017 marks the 20th anniversary of the molecular cloning of the long sought-after capsaicin...
Transient Receptor Potential Vanilloid 4 (TRPV4) is a broadly expressed, polymodally gated ion chann...
More than 30 different Transient Receptor Potential channels (TRP) have been identified in mammals a...
Abstract: There is rapidly growing evidence indicating multiple and important roles of Ca2+-permeabl...
Abstract. Ca2+ channel antagonists acting on electrically-excitable cells have proved to be valuable...
Novel effective therapeutic agents are actively sought for the treatment of a broad spectrum of resp...
Cation channels are of fundamental importance in regulating the function of airway smooth cells espe...
The lungs are essential for gas exchange and serve as the gateways of our body to the external envir...
Transient Receptor Potential Ankyrin 1 (TRPA1) ion channel is expressed abundantly on the C fibers t...
AbstractTransient receptor potential vanilloid type channels (TRPVs) are expressed in several cell t...
Although the TRPC members of the mammalian transient receptor potential TRP cation channel family we...
The mammalian transient receptor potential (TRP) superfamily consists of 28 mammalian TRP cation cha...
© 2015, National Research Council of Canada. All rights reserved. Airway smooth muscle (ASM) contrac...
Transient receptor potential (TRP) channels are a family of functionally diverse and widely expresse...
Cough is the most common reason for patients to visit a primary care physician, yet it remains an un...
The year 2017 marks the 20th anniversary of the molecular cloning of the long sought-after capsaicin...
Transient Receptor Potential Vanilloid 4 (TRPV4) is a broadly expressed, polymodally gated ion chann...
More than 30 different Transient Receptor Potential channels (TRP) have been identified in mammals a...
Abstract: There is rapidly growing evidence indicating multiple and important roles of Ca2+-permeabl...
Abstract. Ca2+ channel antagonists acting on electrically-excitable cells have proved to be valuable...