Add to ORKGA series of N1-substituted-4-alkoxybenzamidines was synthesized and tested in vitro for their inhibitory effects on blood coagulation and agonist induced platelet aggregation. The antiarrhythmic activity against chloroform-induced arrhythmias in mice was also evaluated. The biological activity of the title compounds is reported in comparison with that of procainamide; among the new products described, IVi and IVe were found to have the most potent anti-platelet and antiarrhythmic activity, respectively. The structure-activity relationships are discussed
Antiaggregation activity of first synthesized benzimidazole and xantine derivatives has been studied...
Abstract: A series of some novel n-(anilinocarbonothioyl) benzamide and heterocyclic based thiourea ...
In an effort to develop potent antithrombotic agents, a series of novel 3-carboxamide-benzocoumarin ...
Three amidino- and ten non-amidinobenzamides were synthesized as 3-aminobenzoic acid scaffold-based ...
We have synthesized N1-substituted benzamidines and polybenzamidines with the aim to produce antitum...
The aim of study was to modify the structure of indoline-2,3-diones and 1,2- benzenedicarboximides u...
The synthesis of a series of alkyl and aryl amides (IV) starting from 5-trans-(3-aminopropoxy)-N-ben...
The synthesis of some N,N-disubstituted 4-amino-5,6,7,8-tetrahydro-3,6- diphenyl-2H-1-benzopyran-2-o...
A series of benzyloxy anilides of nipecotic (5, 6) and isonipecotic (7, 8) acids were synthesized an...
In an effort to develop potent antithrombotic agents, a series of novel 2-aminobenzamide derivatives...
Atherothrombotic coronary artery disease, assocd. with deep vein thrombosis, is one of the most comm...
A set of 2-[4-(dialkylaminoalkoxy)phenyl]benzotriazoles and corresponding N-oxides was prepared. In ...
As part of our program toward designing potassium channel openers, the synthesis of a novel series o...
On the pattern of well known dialkylaminoacyl anilides, a set of N-homolupinanoyl anilides was prepa...
The synthesis of new benzylidenaminoguanidine compounds is described. Some of these compounds were t...
Antiaggregation activity of first synthesized benzimidazole and xantine derivatives has been studied...
Abstract: A series of some novel n-(anilinocarbonothioyl) benzamide and heterocyclic based thiourea ...
In an effort to develop potent antithrombotic agents, a series of novel 3-carboxamide-benzocoumarin ...
Three amidino- and ten non-amidinobenzamides were synthesized as 3-aminobenzoic acid scaffold-based ...
We have synthesized N1-substituted benzamidines and polybenzamidines with the aim to produce antitum...
The aim of study was to modify the structure of indoline-2,3-diones and 1,2- benzenedicarboximides u...
The synthesis of a series of alkyl and aryl amides (IV) starting from 5-trans-(3-aminopropoxy)-N-ben...
The synthesis of some N,N-disubstituted 4-amino-5,6,7,8-tetrahydro-3,6- diphenyl-2H-1-benzopyran-2-o...
A series of benzyloxy anilides of nipecotic (5, 6) and isonipecotic (7, 8) acids were synthesized an...
In an effort to develop potent antithrombotic agents, a series of novel 2-aminobenzamide derivatives...
Atherothrombotic coronary artery disease, assocd. with deep vein thrombosis, is one of the most comm...
A set of 2-[4-(dialkylaminoalkoxy)phenyl]benzotriazoles and corresponding N-oxides was prepared. In ...
As part of our program toward designing potassium channel openers, the synthesis of a novel series o...
On the pattern of well known dialkylaminoacyl anilides, a set of N-homolupinanoyl anilides was prepa...
The synthesis of new benzylidenaminoguanidine compounds is described. Some of these compounds were t...
Antiaggregation activity of first synthesized benzimidazole and xantine derivatives has been studied...
Abstract: A series of some novel n-(anilinocarbonothioyl) benzamide and heterocyclic based thiourea ...
In an effort to develop potent antithrombotic agents, a series of novel 3-carboxamide-benzocoumarin ...