Add to ORKGWe have synthesized N1-substituted benzamidines and polybenzamidines with the aim to produce antitumor drugs retaining differential biological properties with respect to unsubstituted compounds. Antiproliferative activity on in vitro cultured human leukemic cells was exhibited by N1-substituted polybenzamidines, while N1-substituted benzamidines were found to retain very low antitumor effect
Synthesis, DNA binding properties and biol. activity of a series of bis-benzoheterocycle derivs. , s...
A new series of 2,6-dibenzylamino-3,5-dicyanopyridines were synthesized and evaluated for their in v...
The synthesis and biological evaluation of a new series of amine-substituted 2-arylbenzimidazole-4-c...
The cinnamoyl anthranilamides represent a class of biological active substances of great importance ...
Several new benzamides 4a-q were synthesized by stirring in pyridine the acid chlorides 3a-q with th...
Tetra benzamidine derivatives were found to inhibit proteinase activity, cell proliferation and accu...
Several new 2-(2-phenoxyacetamido)benzamides 17a-v, 21 and 22 were synthesized by stirring in pyridi...
A series of benzamide-based histone deacetylases (HDACs) inhibitors possessing N-(aminopyridine) res...
abstract: Continuing work has been done on a novel class of anti-cancer drugs employing a vinylogous...
Natural polyamines are nitrogen-bearing aliphatic chains that play an essential role in cell growth ...
A series of N1-substituted-4-alkoxybenzamidines was synthesized and tested in vitro for their inhibi...
We have recently reported that aromatic polyamidines are powerful inhibitors of in vitro proliferati...
International audienceBackground: The development of small molecules as cancer treatments is still o...
Several new 2-cinnamamido, 2-(3-phenylpropiolamido) and 2-(3-phenylpropanamido)benzamides were synth...
A series of novel N-benzylbenzamide derivatives were designed and synthesized as tubulin polymerizat...
Synthesis, DNA binding properties and biol. activity of a series of bis-benzoheterocycle derivs. , s...
A new series of 2,6-dibenzylamino-3,5-dicyanopyridines were synthesized and evaluated for their in v...
The synthesis and biological evaluation of a new series of amine-substituted 2-arylbenzimidazole-4-c...
The cinnamoyl anthranilamides represent a class of biological active substances of great importance ...
Several new benzamides 4a-q were synthesized by stirring in pyridine the acid chlorides 3a-q with th...
Tetra benzamidine derivatives were found to inhibit proteinase activity, cell proliferation and accu...
Several new 2-(2-phenoxyacetamido)benzamides 17a-v, 21 and 22 were synthesized by stirring in pyridi...
A series of benzamide-based histone deacetylases (HDACs) inhibitors possessing N-(aminopyridine) res...
abstract: Continuing work has been done on a novel class of anti-cancer drugs employing a vinylogous...
Natural polyamines are nitrogen-bearing aliphatic chains that play an essential role in cell growth ...
A series of N1-substituted-4-alkoxybenzamidines was synthesized and tested in vitro for their inhibi...
We have recently reported that aromatic polyamidines are powerful inhibitors of in vitro proliferati...
International audienceBackground: The development of small molecules as cancer treatments is still o...
Several new 2-cinnamamido, 2-(3-phenylpropiolamido) and 2-(3-phenylpropanamido)benzamides were synth...
A series of novel N-benzylbenzamide derivatives were designed and synthesized as tubulin polymerizat...
Synthesis, DNA binding properties and biol. activity of a series of bis-benzoheterocycle derivs. , s...
A new series of 2,6-dibenzylamino-3,5-dicyanopyridines were synthesized and evaluated for their in v...
The synthesis and biological evaluation of a new series of amine-substituted 2-arylbenzimidazole-4-c...